DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dco and Y47G6A.13

DIOPT Version :9

Sequence 1:	NP_001263132.1	Gene:	dco / 43673	FlyBaseID:	FBgn0002413	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_491162.1	Gene:	Y47G6A.13 / 189993	WormBaseID:	WBGene00021639	Length:	468	Species:	Caenorhabditis elegans

Alignment Length:	421	Identity:	109/421 - (25%)
Similarity:	176/421 - (41%)	Gaps:	51/421 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NKYRLGRKIGSGSFGDIYLGTTIN-TGEEVAIKL-----ECIRTKHPQLHIESKFYKTMQGGIGI 65
            :|:|:...:|.|:.|.:|.....| .|...|:|:     |..||...::::.||...:..    :
Worm    23 DKWRIKALLGKGACGVVYKVEDKNRKGYCAAMKVEYDSEEFDRTLQLEVNVLSKLTDSRD----V 83

  Fly    66 PRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIK 130
            .::|..|....|..||..|.|..|..|.....|.|:..|.:.:|...:..:..:|...::|||:|
Worm    84 LKLIDYGKRKLYRYMVTTLCGKDLMALRMKIQRGFNDATAMRVAVFTLYGLKQLHEAGYVHRDVK 148

  Fly   131 PDNFLMGL--GKKGNLVYIIDFGLAKKF---RDARSLKHIPYRENKNLTGTARYASINTHLGIEQ 190
            |.|.:...  |:...::.:||||:|:.|   .|....|..|.|....|.||.||.|:|.|...||
Worm   149 PGNIMTAANKGRDARVMLLIDFGMARTFVMAGDDGKKKLRPMRRRIPLRGTIRYCSMNVHERKEQ 213

  Fly   191 SRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFC 255
            .|.|||.::.|.::|..|| |||..||     .:.|.:|.|| ||..:.|.:..|.|..:...:.
Worm   214 GRCDDLVAMIYSIVYLTLG-LPWSNLK-----DEKEIMSMKK-STKDLALFEDLPDELKSIFEYL 271

  Fly   256 RQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWN--------LLKFGGPRNPQAIQQAQDGAD 312
            |.:.:..||:|..:..|......||...:...::|.        ..:.......:..::.::..:
Worm   272 RTLSYADRPNYEKIYNLLMAAITRLKINFLDPYEWEDDEMERMAKAEKEEKEKEEKEKKEKENKE 336

  Fly   313 GQAGHDAVAAAAAVAAAAAAS---SHQQQQHKVNAALGGGGGSAAQQQLQGGQTLAMLGGNGGGN 374
            .:...|::..|....:|.|.|   ....:|.||.     ...|..|||    .||.:      ..
Worm   337 NELSADSMKTAIPAKSAKAESEVAGEVDEQKKVK-----DNSSGEQQQ----DTLNV------DK 386

  Fly   375 GSQLIGGNGLNMDDSMAATNSSRPPYDTPER 405
            |::||....:....|....||.   |.||.:
Worm   387 GNKLISAKDMASSRSEVNENSQ---YGTPAK 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	85/284 (30%)
Y47G6A.13	NP_491162.1	PKc_like	24..289	CDD:389743	82/275 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820