Protein Alignment dco and T05C12.1

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_495715.1
• Gene: T05C12.1 / 188121
• WormBaseID: WBGene00011466
• Length: 325
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 91/304 - (29%)
• Similarity: 152/304 - (50%)
• Gaps: 37/304 - (12%)

  Fly    11 LGRK--------IGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQ-LHIESKFYKTMQGGIGIP 66
            |||.        |..|.||.:|......|.||||:|:|...|...| :.:|||....|.|....|
 Worm    40 LGRNDIFVVEKMIAGGGFGQVYRARNTETQEEVAVKVERATTNDSQRMILESKVLDDMLGSKHFP 104

  Fly    67 RIIWCGSEGDYNVMVMELLGPSLEDLFNFC-SRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIK 130
            .:.:.|....||.:||::||.::.|:.... :::.|:.:.:.:..|:|..:..:||:.::|||:|
 Worm   105 NVYYIGPYHSYNFIVMQMLGKNIGDIRKMMPNKKISILSSVRIGIQIIEALSLLHSKGWLHRDLK 169

  Fly   131 PDNFLMGLGKKGNLVYIIDFGLAKKFR-DARSLKHIPYRENK---NLTGTARYASINTHLGIEQS 191
            |.|..:||.:|...||::|||:::||| |..||     ||::   ...||.||.|...|...||.
 Worm   170 PTNCCLGLDEKRKTVYLVDFGMSRKFRNDNGSL-----RESRTYCGFRGTTRYCSYRMHDRREQG 229

  Fly   192 RRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCR 256
            ..|||..|.|.|.....|.|||:.:::|::....::|.:.:      .:....||:|.::....|
 Worm   230 PVDDLWCLYYSLGELIEGCLPWRDIESADEMAHVKKILKHE------DIFHSMPSKFASFGRNLR 288

  Fly   257 QMHFDQRPDYCHLRKLFRNLFHRLGFTYDYV-----FDWNLLKF 295
            ::.....|||..    |:|:   |.:...:|     |:|:::.:
 Worm   289 RLRPANTPDYTK----FQNI---LAYCVKFVDDNAEFEWDVMDY 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	88/284 (31%)
T05C12.1	NP_495715.1	Protein Kinases, catalytic domain	46..305	CDD:473864	84/276 (30%)