Protein Alignment dco and K08H2.5

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_001361832.1
• Gene: K08H2.5 / 187176
• WormBaseID: WBGene00010692
• Length: 304
• Species: Caenorhabditis elegans
• Alignment Length: 327
• Identity: 77/327 - (23%)
• Similarity: 125/327 - (38%)
• Gaps: 79/327 - (24%)

  Fly     9 YRLGRKIGSGSFGDIYLGTTINTGEE-VAIK---LE------CIRTKHPQLH-------IESKFY 56
            |::...:|||.:|..:.....::... :|:|   ||      |.:.:...|.       .|...:
 Worm    13 YKIVEVLGSGEYGTAFACVDADSRHSTLALKASNLETIFCENCFKLERTVLQRISTLGTNEKSRF 77

  Fly    57 KTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSR----RFSLKTVLLLADQMISRID 117
            .|:.....:...:.|        :||...|.||.|:   |.|    :||...||.:...:...:.
 Worm    78 PTLVDNFVVDSTLGC--------LVMTKEGDSLGDV---CKRNDPKKFSPTNVLKIMLSVGKSLQ 131

  Fly   118 YIHSRDFIHRDIKPDNFLMGLG-KKGNLVYIIDFGLAKKFRDARS--LKHIPYRE-NKNLTGTAR 178
            .|||..:|||||..:|.|.... ...:...:||:|:.||||:.|.  :|:.|.|: |....|
 Worm   132 TIHSLGYIHRDIHWNNVLFAKTITPASPCKLIDYGVGKKFRNRRGNYVKNRPQRDVNFKECG--- 193

  Fly   179 YASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAAN-KRQKYERISEKKLSTSIVVLCK 242
            :.|.|..:|...:.:||..||.::            |||.:. ...:...:||.:....|..|
 Worm   194 HVSWNVMMGGVPNLKDDFSSLMFL------------GLKISGISSLEIGSVSEVRHQKMIFEL-- 244

  Fly   243 GFPSEFVNYLNF-----CRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQ 302
             .||.|:..:.:     |..:..|...                 |.|..||  |.:|.|.|.:.:
 Worm   245 -DPSRFLRSVPWLLKVACVIVDSDAEK-----------------FNYAGVF--NAIKQGFPFDEE 289

  Fly   303 AI 304
            .|
 Worm   290 EI 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	68/303 (22%)
K08H2.5	NP_001361832.1	Protein Kinases, catalytic domain	12..>185	CDD:473864	46/182 (25%)