Protein Alignment dco and C05C12.1

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_502112.1
• Gene: C05C12.1 / 178032
• WormBaseID: WBGene00007335
• Length: 405
• Species: Caenorhabditis elegans
• Alignment Length: 318
• Identity: 80/318 - (25%)
• Similarity: 144/318 - (45%)
• Gaps: 65/318 - (20%)

  Fly     9 YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIR--------TKHPQLHIE-----SKFYKTMQ 60
            |::...||.|::|.::  ......::.|:|:|..|        ||..::.:|     :||:...:
 Worm    25 YQVVESIGEGAYGQVF--KVSKNAKKYAMKVEPNRLDGGPASITKEIEVMMELNNRGAKFFPIFE 87

  Fly    61 GGIGIPRIIWCGSEGDYNVMVMELLGPSLEDL-FNFCS-RRFSLKTVLLLADQMISRIDYIHSRD 123
            .|         |.|..::::||.|||.:|:.| ...|: :..:..|...:..|.:..:..:|...
 Worm    88 TG---------GREPKFHMVVMTLLGENLQVLRMKGCNPKACTPGTWSRIGIQCLFVVKQMHDCG 143

  Fly   124 FIHRDIKPDNFLMGLGKKG---NLVYIIDFGLAKKFRDARSLKHIP--------YRENK----NL 173
            .:|.|:||.||:.|...:.   .:.|:||||:::||  .|.:|..|        :|..|    :|
 Worm   144 ILHHDLKPTNFVWGQSDEALTCRVFYLIDFGISRKF--IRHVKGTPINQQNGFEFRTEKKKVHSL 206

  Fly   174 TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIV 238
            .||.:|.|...|...:..|.|||.||.|::... :..|||:.|:|       :.:...||.:.:
 Worm   207 VGTPKYTSPKAHAMADLGRGDDLWSLMYMIAEL-VKPLPWEILEA-------KMLENTKLKSKL- 262

  Fly   239 VLCK------GFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDW 290
               |      || .:....|:.|.   |:..|:|..:...|:.:|::.|.::...:||
 Worm   263 ---KDHFGMDGF-GKIETMLHACT---FNSFPNYEMIYLAFKEVFNKSGVSWLDPYDW 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	77/308 (25%)
C05C12.1	NP_502112.1	Protein Kinases, catalytic domain	25..293	CDD:473864	75/296 (25%)