Protein Alignment dco and ttbk-4

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_501824.1
• Gene: ttbk-4 / 177871
• WormBaseID: WBGene00012169
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 100/324 - (30%)
• Similarity: 144/324 - (44%)
• Gaps: 65/324 - (20%)

  Fly     6 GNKY---RLGRKIGSGSFGDIYLGTTINTGEEV--------------AIKLEC-----IRTKHPQ 48
            |.|:   ::|:.|..|.||.:|:.|:|:..::|              |||||.     :....|.
 Worm    18 GKKFGDWKIGKTIDEGGFGKVYIATSISDPKKVAALKAESNEIEGGSAIKLEAMILNKLNANGPV 82

  Fly    49 LHIESKFYKTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFN---FCSRRFSLKTVLLLAD 110
            .|              ||.:..|.....|..|||.|||.:|..|.:   ..:..||..|...:..
 Worm    83 PH--------------IPVVHLCAKRKLYCYMVMTLLGRNLRKLKSTNLVVNNGFSRGTWSRIGI 133

  Fly   111 QMISRIDYIHSRDFIHRDIKPDNFLMGL---GKKGNLVYIIDFGLAKKFRDARSLKHIPYRENK- 171
            |.:..:.|:|...|||||:||.|||:|.   .::..:|:|:|||||:.|    ::.|.  ||||
 Worm   134 QCLYALKYVHDNGFIHRDVKPQNFLLGNETDSERARIVHILDFGLARPF----AVFHA--RENKW 192

  Fly   172 ---------NLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLG-ALPWQGLKAANKRQKYE 226
                     ...||.||.|.|.||..||.|.||:.||.||::..|.| |||||      ...:.|
 Worm   193 IARRARGTAEFRGTLRYTSPNVHLRKEQGRVDDVWSLLYVIIELNGGKALPWQ------TDSQRE 251

  Fly   227 RISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDW 290
            |:.:.||:....|:....|:.....:.....:.:.|||||..:.|.|..:......|....:||
 Worm   252 RVEQMKLNLPAKVVMSNMPACMDKVMPHLASLDYYQRPDYHMIFKCFWQVMENEKITPSSKYDW 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	96/312 (31%)
ttbk-4	NP_501824.1	Protein Kinases, catalytic domain	24..298	CDD:473864	94/299 (31%)