Protein Alignment dco and C49C8.1

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_501483.2
• Gene: C49C8.1 / 177670
• WormBaseID: WBGene00016765
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 116/537 - (21%)
• Similarity: 182/537 - (33%)
• Gaps: 185/537 - (34%)

  Fly     7 NKYRLGRKIGSGSFGDIY-------------LGTTINTGEEVAIKLECIRTKHPQLHIESKFYKT 58
            |.|.:..||..|.||.::             |.:....|.. |||||        :::.|:..|.
 Worm    25 NDYEIVSKIDEGGFGQVFKVTKDHKTFYAMKLESNFQVGGS-AIKLE--------INVLSQLPKN 80

  Fly    59 MQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRR--FSLKTVLLLADQMISRIDYIHS 121
            ..    .|.:|..|....|:.:|:||||.:|:.|.......  ||..|...:..|.:..:..:|.
 Worm    81 TV----FPELICGGKRPRYHFLVLELLGDNLKALKAQSPNPSVFSDGTWSRIGIQCLYAMKMMHD 141

  Fly   122 RDFIHRDIKPDNFLMGLG----KKGNLVYIIDFGLAKKF-------------------------- 156
            ..|:||||||.||.:|..    .:...|.:.|||||:||
 Worm   142 SGFVHRDIKPSNFAIGYSTASESRSRRVLLFDFGLARKFVKKEKNLAPIVTKKESKISKSKTLPS 206

  Fly   157 --------------------RDARSLK-------HIP------------------------YREN 170
                                |.|..:|       .||                        .|.:
 Worm   207 KGPSTKSKDLKPGRSKPILNRKAEQMKIKKNFNMLIPPKSIDQSQRTAEEKVDDEEFTFRRARPH 271

  Fly   171 KNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPW--------QGLKAANKRQKYER 227
            .:..||.:|||.|.||.:|..|.||:.||.|::..|.: .|||        :.||  |:......
 Worm   272 TDFRGTFQYASPNAHLQLELGRHDDIWSLMYMVAEFFV-ELPWTSNEEIALEELK--NQSSILRL 333

  Fly   228 ISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNL 292
            .|:.|..:.:....:|...|....|..|   ::...|.|..:.:.|::...:...|:...:||..
 Worm   334 FSDDKNPSRLTPEMRGQLDEIDKNLKSC---NYYSSPKYDIVYQFFKDSMTKAKVTWTTPYDWET 395

  Fly   293 L---------KFGGPR----NPQAIQQAQDGADGQAGH-DAV---AAAAAVAAAAAASSHQQQQH 340
            :         |..|.|    ||        ||..:.|. ||:   ..:..::...::|.|.:...
 Worm   396 IGKSSEDFSKKSNGKRAVWENP--------GAFFKKGRWDALPLPLQSPHISIRKSSSKHPKPSA 452

  Fly   341 KVNAALGGGGGSAAQQQLQGGQTLAMLGGNGGGNGSQLIGGNGLNMDDSMAATNSSRPPYDTPER 405
            |       |...|.|.::|                       ..:.:||:.|..:..|...:.:
 Worm   453 K-------GSKKAVQARIQ-----------------------NFSKEDSVEADEAPTPMLKSTK- 486

  Fly   406 RPSIRMRQGGGGGGGGV 422
                  :.|.||..||:
 Worm   487 ------KDGMGGQKGGL 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	86/377 (23%)
C49C8.1	NP_501483.2	Protein Kinases, catalytic domain	27..377	CDD:473864	85/368 (23%)