Protein Alignment dco and F36H12.9

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_500758.1
• Gene: F36H12.9 / 177303
• WormBaseID: WBGene00018123
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 343
• Identity: 93/343 - (27%)
• Similarity: 157/343 - (45%)
• Gaps: 73/343 - (21%)

  Fly     7 NKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIPRIIWC 71
            :||::...:|.|.:|.:|....::..|:.|||.|........|.::.   ..|:|...|....:|
 Worm    22 DKYKVIALLGKGGYGAVYSVLRLSDMEKFAIKCEKATAGKKVLLMDC---NVMKGATQIKSRHFC 83

  Fly    72 ------GSEGDYNVMVMELLGPSLEDLFNFCSR---RFSLKTVLLLADQMISRIDYIHSRDFIHR 127
                  ..:..:|.:||:|:|.:|.||..  .|   :|::.|.|..|.|.:..|:::||..::||
 Worm    84 TVLDRANVKDRFNFIVMKLIGKNLWDLRQ--DRGDGKFTMGTSLKAASQCLVSIEHLHSFGYLHR 146

  Fly   128 DIKPDNFLMGLGKKGN---LVYIIDFGLAKKF------RDARSLK-HIPYRENKNLTGTARYASI 182
            ||||.||..| .|:.|   :::::||||.:::      :|.|:.: ..|:|      ||.|||.:
 Worm   147 DIKPGNFAAG-RKESNEHHVIFMLDFGLCREYVKRAEGKDLRAARTTAPFR------GTTRYAPL 204

  Fly   183 NTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQ----KYERISEKKLSTSIVVLCKG 243
            .:.|..:|||:||:||..|:::.:..|.|||:.|||.::.:    |.:..::..:....:.||.
 Worm   205 ASMLQQDQSRKDDIESWLYMVVEWTSGGLPWRKLKAHDREKVLQYKQDLRTKPDILDDFLFLCP- 268

  Fly   244 FPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYV--------------FDWNLLK 294
             ..||...|.:...:.:...|||              .|.|..|              .||:
 Worm   269 -KKEFTRILKYLDTLGYYAVPDY--------------KFIYFCVQHAANANKIKDADPLDWD--- 315

  Fly   295 FGGPRNPQ--AIQQAQDG 310
               |..|.  .|:|..||
 Worm   316 ---PETPYMGPIEQPGDG 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	82/296 (28%)
F36H12.9	NP_500758.1	Protein Kinases, catalytic domain	23..296	CDD:473864	84/300 (28%)