DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dco and C56C10.6

DIOPT Version :9

Sequence 1:	NP_001263132.1	Gene:	dco / 43673	FlyBaseID:	FBgn0002413	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_495333.1	Gene:	C56C10.6 / 174087	WormBaseID:	WBGene00016963	Length:	422	Species:	Caenorhabditis elegans

Alignment Length:	306	Identity:	92/306 - (30%)
Similarity:	148/306 - (48%)	Gaps:	34/306 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLE-------CIRTKHPQLHIESKFYKTMQGG 62
            ||..:::.||:|.|..|.:||...:....|.|:|.|       |:      |.:|....|.:.|.
Worm    20 VGCSWQVIRKLGEGGCGSVYLVKNLEDETEAAMKAESNGAAGGCV------LKLEVAILKKLSGK 78

  Fly    63 IGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHR 127
            ..:.:.::.....|:..::|.|||.||..:....:|:.::.:.:.:|..::..:..||...||||
Worm    79 PHVCQFLFAARLTDFTYVIMTLLGESLNKIVKRIARQITVSSQVRIAANVLFCLKQIHDIGFIHR 143

  Fly   128 DIKPDNFLMGLGKKGN-----LVYIIDFGLAKKF------RDARSLKHIPYRENKNLTGTARYAS 181
            |:||.|  |.||.|.|     ..:::|||||::|      :.::.:...| ||.....||.||.|
Worm   144 DLKPAN--MALGYKTNNDECRFFHVLDFGLARQFVVSQSDQPSKLMMRRP-RERSLFRGTTRYCS 205

  Fly   182 INTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPS 246
            |..|...||.|.|||.|:.|:|.... |.|||.  ..::||...|.   |:|.:..||| :..|.
Worm   206 IRMHDRAEQGRVDDLWSMVYLLAELR-GPLPWS--SQSDKRVVGEM---KRLHSDEVVL-QNSPM 263

  Fly   247 EFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNL 292
            ||:....:.|.:.:..||||..:..|..::..:..|.::..|||.:
Worm   264 EFLEIAKYLRSLTYFHRPDYHKIFMLLISVMSKGKFAWNDPFDWEM 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	86/291 (30%)
C56C10.6	NP_495333.1	PKc_like	24..290	CDD:389743	85/281 (30%)
C56C10.6	NP_495333.1	CAF-1_p150	322..>407	CDD:371622
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810