Protein Alignment dco and vrk-1

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_495185.1
• Gene: vrk-1 / 174004
• WormBaseID: WBGene00017895
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 315
• Identity: 84/315 - (26%)
• Similarity: 136/315 - (43%)
• Gaps: 63/315 - (20%)

  Fly     2 ELRVGNK--------YRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLH-------- 50
            |:|||:|        :.:|::..:|.||.|:..|.....:::.:|:| ..|..|.|.
 Worm    17 EVRVGHKINDISKKTFIVGKQFATGGFGRIHTCTEEGKSQQMVMKIE-PSTNGPLLTEVVVFNRI 80

  Fly    51 -----IESKFYKTMQGGIGIPRIIWCG-----SEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTV 105
                 |||...|.....||:|.:|..|     || ....|::.....|||.:........::|..
 Worm    81 LKKELIESYKKKKKISWIGLPYLIANGYFTYESE-KMRYMIIPKYATSLEAVRETNGGTLAMKDS 144

  Fly   106 LLLADQMISRIDYIHSRDFIHRDIKPDNFLMGLGKKGNLVY----IIDFGLAKKFRDARSLKHIP 166
            |.:|..::..::|:|..|:.|.|:|..|.|  |.|:|  ||    ::|||||.     |:..::.
 Worm   145 LTVASCILDALEYLHESDYAHADVKAANIL--LEKQG--VYSTAVLVDFGLAH-----RTTNNVD 200

  Fly   167 YRENKNL-TGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGL-----KAANKRQKY 225
            ..:.|.. .||..:.|.:.|.|...|.|.|:|.|.|.||.:..|.|||..|     |..:.:||:
 Worm   201 KPDKKRAHNGTCIFTSTDAHRGNNPSFRGDIEILAYNLMMWATGTLPWMALESSPEKVFDAKQKF 265

  Fly   226 --------ERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKL 272
                    :.:  .|..:|.||.|      ..:..:...:.::..:.|...|:||
 Worm   266 IAGLPGTLQNV--LKNESSAVVGC------IASMFDISMKTNYTDKVDMGKLKKL 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	80/309 (26%)
vrk-1	NP_495185.1	Protein Kinases, catalytic domain	26..312	CDD:473864	77/304 (25%)
		PLN02967	341..>445	CDD:215521