Protein Alignment dco and Y71F9AL.2

DIOPT Version :10

• Sequence 1: NP_524602.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_491074.1
• Gene: Y71F9AL.2 / 171863
• WormBaseID: WBGene00022108
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 112/495 - (22%)
• Similarity: 178/495 - (35%)
• Gaps: 158/495 - (31%)

  Fly     5 VGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGI---- 65
            |.|.|:|.:||..|.||.:: ..|.:.....|:||            ||.|   ::||..|
 Worm    39 VVNGYKLVKKIDEGGFGQVF-KVTKDDKTFYAMKL------------ESNF---LEGGSAIKLEL 87

  Fly    66 ------------PRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRR--FSLKTVLLLADQMISRI 116
                        |.::..|....|..:|:||||.:|:.|.:..:..  :|..|...:..|.:..|
 Worm    88 NVLSQLPKNSVFPALVCGGRRARYQFLVLELLGDNLKVLKSQSTNPEVWSDGTWSRVGIQCLFAI 152

  Fly   117 DYIHSRDFIHRDIKPDNFLMGLGKKGNL----VYIIDFGLAKKF--------------------- 156
            ..:|...|:||||||.||.:|......:    :.:.|||||:||
 Worm   153 KVMHDAGFVHRDIKPSNFAIGFSATSEIRSRRILLFDFGLARKFVRKLPQASVSVKKDVSKAKSA 217

  Fly   157 -----------------------RD--------------------ARSLKHIPYRE--------- 169
                                   ||                    .|:::.||..|
 Worm   218 LLKNSSTTKAVAKLRGKPPTHRIRDPMKMKKSAGSAAKTKNKDPSQRAMEEIPEHEGYKFRVARP 282

  Fly   170 NKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLKAA------NKRQKYERI 228
            ..:..||.:|||.|.|:.||..|.||:.||.|::.. :...|||.|.:..      |:.......
 Worm   283 RTDFRGTHQYASPNAHMLIELGRHDDIWSLMYMVAE-SFVELPWTGCEETEVEHYKNQSTILRLF 346

  Fly   229 SEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNL- 292
            |::|..|.:....:....|..:.|...:  ::|. |:|..:.:.|::...:...|:|..|||.:
 Worm   347 SDEKNPTRLNADMRRQLDEIYSMLKASK--YYDS-PNYDAVYQFFKDSMAKAKVTWDTPFDWEIG 408

  Fly   293 ------------LKFGGP-RNPQAIQQAQDGADGQAGHDA-VAAAAAVAAAAAASSHQQQQHKVN 343
                        .|.||| .||        |...:.|..| :.....:...:|.:|.:|...|.:
 Worm   409 NTLSEETSKGVKRKMGGPWENP--------GLFFKKGRWAGLKFIPELTPKSAPTSKKQNLPKSS 465

  Fly   344 AALGGGGGSAAQQQLQGGQTLAMLGGNGGGNGSQLIGGNG 383
            :.    ||.||:|          :......||..::...|
 Worm   466 SK----GGRAARQ----------MSKEDSANGDDVVVNQG 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_524602.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	84/374 (22%)
Y71F9AL.2	NP_491074.1	Protein Kinases, catalytic domain	43..389	CDD:473864	83/365 (23%)