Protein Alignment dco and TTBK2

DIOPT Version :9

• Sequence 1: NP_001263132.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: XP_005254228.1
• Gene: TTBK2 / 146057
• HGNCID: 19141
• Length: 1250
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 110/370 - (29%)
• Similarity: 150/370 - (40%)
• Gaps: 96/370 - (25%)

  Fly    57 KTMQGGIGIPRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSR-RFSLKTVLLLADQMISRIDYIH 120
            |...|...:.|.|.||....:|.:||:|.|.:|.||....|| .|::.|.|.|..|::..|:.||
Human    75 KMESGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIH 139

  Fly   121 SRDFIHRDIKPDNFLMG-LGKKGNLVYIIDFGLAKKFR----DARSLKHIPYRENKNLTGTARYA 180
            |..|:||||||.||.|| ........|::|||||::|.    |.|     |.|......||.|||
Human   140 SVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVR-----PPRAVAGFRGTVRYA 199

  Fly   181 SINTHLGIEQSRRDDLESLGYVLMYFNLGALPWQGLK----AANKRQKYERISEKKLSTSIVVLC 241
            |||.|...|..|.|||.||.|:|:.|.:|.|||:.:|    ..:.:::|:.          .::.
Human   200 SINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDH----------RLML 254

  Fly   242 KGFPSEFVNYLNFCRQMHFDQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGG--------- 297
            |..|.||..:|:....:.:..:|||..|..:|.|.....|......|||.  |.|.
Human   255 KHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE--KTGNDGSLTTTTT 317

  Fly   298 ---PR-----NPQAI-----------------------QQAQDGAD------------GQAGH-- 317
               |:     .|.||                       :|..||.:            |..||
Human   318 STTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPVGVSPDKLPGSLGHPR 382

  Fly   318 ----------DA----VAAAAAVAAAAAASSHQQQQHKVNA-ALG 347
                      ||    :......||....:||.|....:|| :||
Human   383 PQEKDVWEEMDANKNKIKLGICKAATEEENSHGQANGLLNAPSLG 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	83/234 (35%)
TTBK2	XP_005254228.1	PKc_like	75..287	CDD:304357	81/226 (36%)
		SPS1	78..>267	CDD:223589	76/203 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810