Protein Alignment dco and CSNK1D

DIOPT Version :9

• Sequence 1: NP_001263132.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: XP_005256393.1
• Gene: CSNK1D / 1453
• HGNCID: 2452
• Length: 450
• Species: Homo sapiens
• Alignment Length: 415
• Identity: 278/415 - (66%)
• Similarity: 313/415 - (75%)
• Gaps: 40/415 - (9%)

  Fly     1 MELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGI 65
            |||||||:|||||||||||||||||||.|..||||||||||::|||||||||||.||.||||:||
Human     1 MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGI 65

  Fly    66 PRIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIK 130
            |.|.|||:|||||||||||||||||||||||||:|||||||||||||||||:||||::|||||:|
Human    66 PTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVK 130

  Fly   131 PDNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195
            |||||||||||||||||||||||||:||||:.:||||||||||||||||||||||||||||||||
Human   131 PDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDD 195

  Fly   196 LESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHF 260
            ||||||||||||||:|||||||||.||||||||||||:||.|.|||||:||||..||||||.:.|
Human   196 LESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRF 260

  Fly   261 DQRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQDGADGQAGHDAVAAAAA 325
            |.:|||.:||:||||||||.||:||||||||:||||..|       |.|.|:.:
Human   261 DDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASR-------AADDAERE----------- 307

  Fly   326 VAAAAAASSHQQQQHKVNAALGGGGGSAAQQQLQGGQTLAMLGGNGGGNGSQLIGGNGLNMDDSM 390
                 .....::.:|..|.|..|...:|                :|...|:|.:.........|.
Human   308 -----RRDREERLRHSRNPATRGLPSTA----------------SGRLRGTQEVAPPTPLTPTSH 351

  Fly   391 AATNSSRPPYDTP-ERRPSIRMRQG 414
            .|..|.||..... ||:.|:|:.:|
Human   352 TANTSPRPVSGMERERKVSMRLHRG 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	235/273 (86%)
CSNK1D	XP_005256393.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	235/273 (86%)
		TyrKc	10..273	CDD:197581	226/262 (86%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155506
Domainoid	1	1.000	406	1.000	Domainoid score	I709
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	552	1.000	Inparanoid score	I1127
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	1	1.000	-	-		otm41979
orthoMCL	1	0.900	-	-		OOG6_100396
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3408
SonicParanoid	1	1.000	-	-		X224
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.700