Protein Alignment dco and CSNK1A1L

DIOPT Version :9

• Sequence 1: NP_001263132.1
• Gene: dco / 43673
• FlyBaseID: FBgn0002413
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_660204.2
• Gene: CSNK1A1L / 122011
• HGNCID: 20289
• Length: 337
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 209/338 - (61%)
• Similarity: 254/338 - (75%)
• Gaps: 29/338 - (8%)

  Fly     2 ELRVGNKYRLGRKIGSGSFGDIYLGTTINTGEEVAIKLECIRTKHPQLHIESKFYKTMQGGIGIP 66
            ||.||.||:|.||||||||||:|||.|...||:||:|||..:.|||||..|||.|..:|||:|||
Human    10 ELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIP 74

  Fly    67 RIIWCGSEGDYNVMVMELLGPSLEDLFNFCSRRFSLKTVLLLADQMISRIDYIHSRDFIHRDIKP 131
            .:.|.|.|.|.||:||:|||||||||||||||||::||||:|||||||||:|:|:::|:||||||
Human    75 HMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKP 139

  Fly   132 DNFLMGLGKKGNLVYIIDFGLAKKFRDARSLKHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196
            ||||||.|:..|.:::||||||||:||.|:.:||||||:|:|.||.||||||.|||||||||||:
Human   140 DNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDM 204

  Fly   197 ESLGYVLMYFNLGALPWQGLKAANKRQKYERISEKKLSTSIVVLCKGFPSEFVNYLNFCRQMHFD 261
            ||||||.||||..:||||||:|..|:||||:|||||:||.:.|||||||:||..|||:||.:.|:
Human   205 ESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFE 269

  Fly   262 QRPDYCHLRKLFRNLFHRLGFTYDYVFDWNLLKFGGPRNPQAIQQAQDGADGQAGHDAVAAAAAV 326
            :.|||.:||:|||.||..|...|||.|||.:||      .:|.||
Human   270 EVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLK------QKAAQQ-------------------- 308

  Fly   327 AAAAAASSHQQQQ 339
               ||:||.|.||
Human   309 ---AASSSGQGQQ 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dco	NP_001263132.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	187/273 (68%)
CSNK1A1L	NP_660204.2	STKc_CK1_alpha	16..281	CDD:271030	181/264 (69%)
		SPS1	16..>239	CDD:223589	156/222 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..337		7/10 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54222
OrthoDB	1	1.010	-	-		D1097975at2759
OrthoFinder	1	1.000	-	-		FOG0000297
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100396
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X224
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.730