Protein Alignment Chchd3 and CHCHD6

DIOPT Version :9

• Sequence 1: NP_651838.1
• Gene: Chchd3 / 43672
• FlyBaseID: FBgn0010808
• Length: 223
• Species: Drosophila melanogaster
• Sequence 2: NP_001307539.1
• Gene: CHCHD6 / 84303
• HGNCID: 28184
• Length: 236
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 49/195 - (25%)
• Similarity: 89/195 - (45%)
• Gaps: 28/195 - (14%)

  Fly     3 ARQSQSREPRTVSMENPTPAGVIDISDDVVKRLKAGISQQAREHAAAAEESKPVPKPTTKAAAKP 67
            |...:|..||:.|.....|:|           :|.|:.:..:||||..::...|.|...:||.|
Human    62 APHKESTLPRSGSSGGQQPSG-----------MKEGVKRYEQEHAAIQDKLFQVAKREREAATK- 114

  Fly    68 AASSPAASPAPKVS-SYPAAVPIYVQGGGHTISAADVQRQMNQELIKNDELWKERMAKLEENLKK 131
              .|.|:.|..:.| |:.....:.:|       |.:::.: ..||.:.|..:||::.::|....:
Human   115 --HSKASLPTGEGSISHEEQKSVRLQ-------ARELESR-EAELRRRDTFYKEQLERIERKNAE 169

  Fly   132 TNTILEKEYANAVENVHKRFVSTASSHKVPP-CQDLKSQLLACYRAHPGETLKCIEEVAQFRQCI 195
            ...:..:::..|...:.    ||....:|.| |..|::|:|.|||..|.|.|.|.:.|..:::|:
Human   170 MYKLSSEQFHEAASKME----STIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCV 230

  Fly   196  195
            Human   231  230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chchd3	NP_651838.1	DUF1690	<103..193	CDD:285231	23/90 (26%)
		CHCH	163..195	CDD:284221	12/31 (39%)
CHCHD6	NP_001307539.1	DUF737	17..190	CDD:283062	34/153 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..90		9/38 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..132		9/28 (32%)
		Cx9C motif 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU01150	198..208		4/9 (44%)
		Cx9C motif 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU01150	219..229		2/9 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4083
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	56	1.000	Inparanoid score	I5427
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002524
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	6	5.820