Protein Alignment Alp4 and Alpi

DIOPT Version :9

• Sequence 1: NP_524601.2
• Gene: Alp4 / 43671
• FlyBaseID: FBgn0016123
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001074551.1
• Gene: Alpi / 76768
• MGIID: 1924018
• Length: 554
• Species: Mus musculus
• Alignment Length: 508
• Identity: 226/508 - (44%)
• Similarity: 285/508 - (56%)
• Gaps: 51/508 - (10%)

  Fly    50 EPEDAEFWHNVGLRQLEKTIKQAQRVKEDSYQKKARNIIIFIGDGMGISTISAGRIYKGQYLKHG 114
            |.|:..||:......|: ..|:.|.:     |..|:|:|||:|||||:.|::|.||.|||...|
Mouse    25 EEENPAFWNKKAAEALD-AAKKLQPI-----QTSAKNLIIFLGDGMGVPTVTATRILKGQLEGH- 82

  Fly   115 YGEEETLVFDDFPNTGMAKTYNVDKQVPDSAGTATAIFSGSKTHYGAIGMDATR--SKKNGQQG- 176
            .|.|..|..|.||...::||||||:|||||||||||...|.|.:|..||:.|..  .:.|...|
Mouse    83 LGPETPLAMDLFPYMALSKTYNVDRQVPDSAGTATAYLCGVKANYKTIGLSAAARLDQCNTTFGN 147

  Fly   177 RVQSVMEWAQKEGKRTGVVTTTRITHATPAATYAHIYDRDWECDTEVPAESV--GFHVDIARQLV 239
            .|.|||..|:|.||..|||||||:.||:||.||||..:|:|..|.|:||.::  |.. |||.||:
Mouse   148 EVFSVMYRAKKAGKSVGVVTTTRVQHASPAGTYAHTVNRNWYSDAEMPASALQDGCK-DIATQLI 211

  Fly   240 ENAPGNRFNVILGGG---MSPMGILNASEVKTTIFEGPTET--ICTRGDNRNLPAEWLAHHANDT 299
            .|..   .:||||||   |.|.|        |...|.|:::  ..||.|::||...||:.|..
Mouse   212 SNMD---IDVILGGGRKFMFPKG--------TPDPEYPSDSNQSGTRLDDQNLVQTWLSKHQG-- 263

  Fly   300 VPPALVHNRKDLLNVNV-KKVDHLMGLFRNNHITYSIAREAG-EPSLQEMTETALGILERGDESN 362
              ...|.||.:|:..:. ..|.||||||....:.|...|... :|||.||||.|:.:|.|..:
Mouse   264 --ARYVWNRSELIQASQDPAVTHLMGLFEPTEMKYDANRNPSVDPSLAEMTEVAVRMLSRNPQ-- 324

  Fly   363 GFVLLVEGGRIDQGHHMNYARAALHELYEFDLAIQAAVNNTDPDETLILVTADHSHAVTFNGYAL 427
            ||.|.|||||||||||...|..||.|...||.||:.|...|:..:||||:||||||...|.||.|
Mouse   325 GFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEKASQLTNEKDTLILITADHSHVFAFGGYTL 389

  Fly   428 RGADILGTANSHEKNDPMFYETISYANGPGYWDHLANDSRPQNSSNMWMPLKHFTAEERAAPTYR 492
            ||..|.|.|.....:|.. |.:|.|.|||||  .|.:.:||           :.|..:...|.|:
Mouse   390 RGTSIFGLAPLKALDDKS-YTSILYGNGPGY--ELKSGNRP-----------NVTEAQSVDPNYK 440

  Fly   493 HLATVPRKDETHGGEDVAVFAYGPGSSLIRGVFEQNYLAYVMSYAGCLGPAKD 545
            ..|.||...|||||||||:||.||.:.|:.||.||||:|:||::||||.|..|
Mouse   441 QQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAGCLEPYTD 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp4	NP_524601.2	PhoA	60..534	CDD:224699	214/485 (44%)
		alkPPc	85..541	CDD:214515	214/467 (46%)
Alpi	NP_001074551.1	Alk_phosphatase	53..488	CDD:278666	214/467 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847897
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H122414
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	1	1.010	-	-		D216917at33208
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.660