Protein Alignment Alp4 and Alppl2

DIOPT Version :9

• Sequence 1: NP_524601.2
• Gene: Alp4 / 43671
• FlyBaseID: FBgn0016123
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_031459.3
• Gene: Alppl2 / 11650
• MGIID: 108009
• Length: 529
• Species: Mus musculus
• Alignment Length: 508
• Identity: 226/508 - (44%)
• Similarity: 289/508 - (56%)
• Gaps: 51/508 - (10%)

  Fly    50 EPEDAEFWHNVGLRQLEKTIKQAQRVKEDSYQKKARNIIIFIGDGMGISTISAGRIYKGQYLKHG 114
            |.|:..||:    |:..:.:..|:::|  ..|..|:|::|.:|||||:||::|.||.|||...|
Mouse    23 EEENPAFWN----RKAAEALDAAKKLK--PIQTSAKNLVILMGDGMGVSTVTATRILKGQQQGH- 80

  Fly   115 YGEEETLVFDDFPNTGMAKTYNVDKQVPDSAGTATAIFSGSKTHYGAIGMDATR--SKKNGQQG- 176
            .|.|..|..|.||:..::||||.|||:||||||.||...|.||:...||:.|..  ::.|...|
Mouse    81 LGPETQLAMDRFPHMALSKTYNTDKQIPDSAGTGTAFLCGVKTNMKVIGLSAAARFNQCNTTWGN 145

  Fly   177 RVQSVMEWAQKEGKRTGVVTTTRITHATPAATYAHIYDRDWECDTEVPAESV--GFHVDIARQLV 239
            .|.|||..|:|.||..||||||.:.||:||.||||..:|.|..|.::||.::  |.. ||:.||:
Mouse   146 EVVSVMHRAKKAGKSVGVVTTTSVQHASPAGTYAHTVNRGWYSDAQMPASALQDGCK-DISTQLI 209

  Fly   240 ENAPGNRFNVILGGG---MSPMGILNASEVKTTIFEGPTET--ICTRGDNRNLPAEWLAHHANDT 299
            .|..   .:||||||   |.|.|        |...|.||:|  ..||.|.|||..||||.|..
Mouse   210 SNMD---IDVILGGGRKFMFPKG--------TPDQEYPTDTKQAGTRLDGRNLVQEWLAKHQG-- 261

  Fly   300 VPPALVHNRKDLLNVNV-KKVDHLMGLFRNNHITYSIARE-AGEPSLQEMTETALGILERGDESN 362
              ...|.||.:|:..:: :.|.||||||..|.:.|.|.|: |.:|||.||||.|:.:|.|..:
Mouse   262 --ARYVWNRSELIQASLNRSVTHLMGLFEPNDMKYEIHRDPAQDPSLAEMTEVAVRMLSRNPK-- 322

  Fly   363 GFVLLVEGGRIDQGHHMNYARAALHELYEFDLAIQAAVNNTDPDETLILVTADHSHAVTFNGYAL 427
            ||.|.|||||||.|||...|..||.|...||.|:..|...|...:|:|||||||||..:|.||..
Mouse   323 GFYLFVEGGRIDHGHHETVAYRALTEAVMFDSAVDKADKLTSEQDTMILVTADHSHVFSFGGYTQ 387

  Fly   428 RGADILGTANSHEKNDPMFYETISYANGPGYWDHLANDSRPQNSSNMWMPLKHFTAEERAAPTYR 492
            |||.|.|.| ..:..|...:.:|.|.|||||  .|.|.:|..           .|.||.:.|||:
Mouse   388 RGASIFGLA-PFKAEDGKSFTSILYGNGPGY--KLHNGARAD-----------VTEEESSNPTYQ 438

  Fly   493 HLATVPRKDETHGGEDVAVFAYGPGSSLIRGVFEQNYLAYVMSYAGCLGPAKD 545
            ..|.||...|||.|||||:||.||.:.|:.||.||||:|:||::|.||.|..|
Mouse   439 QQAAVPLSSETHSGEDVAIFARGPQAHLVHGVQEQNYIAHVMAFAACLEPYTD 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp4	NP_524601.2	PhoA	60..534	CDD:224699	215/485 (44%)
		alkPPc	85..541	CDD:214515	214/467 (46%)
Alppl2	NP_031459.3	Alk_phosphatase	51..486	CDD:333956	214/467 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847858
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1785
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48882
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100381
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X159
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650