Protein Alignment Alp4 and alpi.2

DIOPT Version :10

• Sequence 1: NP_524601.2
• Gene: Alp4 / 43671
• FlyBaseID: FBgn0016123
• Length: 596
• Species: Drosophila melanogaster
• Sequence 2: NP_001116946.1
• Gene: alpi.2 / 100144722
• XenbaseID: XB-GENE-854953
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 563
• Identity: 212/563 - (37%)
• Similarity: 290/563 - (51%)
• Gaps: 83/563 - (14%)

  Fly    45 VGKTKEPEDAEFWHNVGLRQLEKTIKQAQRVKEDSYQKKARNIIIFIGDGMGISTISAGRIYKGQ 109
            |...:..::.:||::    |.::|:|.|..:...::  :|:|:|:|:|||||::||:|.|||:||
 Frog    33 VSSLEAEKNPKFWND----QAKETLKNALNLNPITH--RAKNLIMFLGDGMGVTTIAAARIYQGQ 91

  Fly   110 YLKHGYGEEETLVFDDFPNTGMAKTYNVDKQVPDSAGTATAIFSGSKTHYGAIGMDA-------T 167
             ::...|||..:..:.||...::|.||||.||||||||.||...|.|.:.|.:|:.|       .
 Frog    92 -VEGQPGEENIMAMEKFPYVALSKVYNVDAQVPDSAGTGTAYLCGVKANSGTLGVSAAAIYGNCV 155

  Fly   168 RSKKNGQQGRVQSVMEWAQKEGKRTGVVTTTRITHATPAATYAHIYDRDWECDTEVPAESVGFHV 232
            .||.|    .|.|::..|:..||..|:|||||:.||:|.|.|||...|:|..|.|:.:..:....
 Frog   156 SSKGN----EVTSILHRAKLAGKSVGIVTTTRVQHASPGAAYAHSASRNWYSDNEMTSAMINNGC 216

  Fly   233 -DIARQLVENAPGNRFNVILGGG---MSPMGILNASEVKTTIFEGPTETICTRGDNRNLPAEWLA 293
             |||.|||.|..   .:||||||   |.|.|..:..      :.|.:.....|.|..||...||:
 Frog   217 KDIAYQLVHNTD---IDVILGGGRAYMYPAGTPDPE------YPGSSADRGLRRDGLNLTDIWLS 272

  Fly   294 HHANDTVPPALVHNRKDLLNVNVKKVDHLMGLFRNNHITYSIAREAG-EPSLQEMTETALGILER 357
            ...|    ...|.|::....|||...|:|||||....:.|.:.|.|. :|||.||||.|:.||.:
 Frog   273 KRQN----ARYVWNKEQFNAVNVDTTDYLMGLFEPKDMKYELNRNASLDPSLAEMTEKAIRILSK 333

  Fly   358 GDESNGFVLLVEGGRIDQGHHMNYARAALHELYEFDLAIQAAVNNTDPDETLILVTADHSHAVTF 422
            ..:  ||.|.|||||||.|||...|:.:|.|..|||.|:......|..:|||.:|||||||..||
 Frog   334 NPK--GFFLFVEGGRIDHGHHDGNAKQSLTEALEFDKAVLRGGQLTQENETLTVVTADHSHVFTF 396

  Fly   423 NGYALRGADILGTANSHEKNDPMFYETISYANGPGYWDHLANDSRPQNSSNMWMPL-----KHFT 482
            .||..||..|.|.|.| ..:|...|.::.|.|||||                  ||     .:.|
 Frog   397 GGYTDRGNSIFGLAPS-LASDRKPYTSLLYGNGPGY------------------PLPDAIRANIT 442

  Fly   483 AEERAAPTYRHLATVPRKDETHGGEDVAVFAYGPGSSLIRGVFEQNYLAYVMSYAGCLGPAKDFD 547
            .....:.:|...|.||...|||||||||:.|.||.:.|..|..||:|:|:||:||.||.|..:
 Frog   443 GVNTGSNSYLQQAAVPVVSETHGGEDVAIMAKGPQAHLFHGFHEQSYIAHVMAYAACLEPYTE-- 505

  Fly   548 DSCEDHKDGQKDRPLDKPNPKRNGATVVGASLIPILTAATAAI 590
              |..                 ||.::..|:::|:|||....|
 Frog   506 --CPP-----------------NGGSIYTATILPLLTACLVCI 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alp4	NP_524601.2	alkPPc	85..541	CDD:214515	193/472 (41%)
alpi.2	NP_001116946.1	Alk_phosphatase	66..500	CDD:395188	193/472 (41%)