Protein Alignment CanA1 and CNA1

DIOPT Version :10

• Sequence 1: NP_524600.3
• Gene: CanA1 / 43670
• FlyBaseID: FBgn0010015
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_013537.1
• Gene: CNA1 / 851153
• SGDID: S000004425
• Length: 553
• Species: Saccharomyces cerevisiae
• Alignment Length: 545
• Identity: 285/545 - (52%)
• Similarity: 376/545 - (68%)
• Gaps: 35/545 - (6%)

  Fly    16 LSK--SSSSDKSAKSSSNSSKSPTAASGNKQKMQYTK---TRERMVDDVPLPPTHKLTMSEVYDD 75
            :||  :||..|..|.:.:..|........|.:::..|   |::|.:..|| ..|.|:...|...|
Yeast     1 MSKDLNSSRIKIIKPNDSYIKVDRKKDLTKYELENGKVISTKDRPIASVP-AITGKIPSDEEVFD 64

  Fly    76 PKTGKPNFDALRQHFLLEGRIEEAVALRIITEGAALLREEKNMIDVEAPITVCGDIHGQFFDLVK 140
            .|||.||...||:||..|||:.:..|::|:......|.:|.|::.::||||:|||||||::||:|
Yeast    65 SKTGLPNHSFLREHFFHEGRLSKEQAIKILNMSTVALSKEPNLLKLKAPITICGDIHGQYYDLLK 129

  Fly   141 LFEVGGPPATTRYLFLGDYVDRGYFSIECVLYLWSLKITYPTTLSLLRGNHECRHLTEYFTFKQE 205
            ||||||.||...|||||||||||.||.||::||:|||:.......:|||||||:|||.|||||.|
Yeast   130 LFEVGGDPAEIDYLFLGDYVDRGAFSFECLIYLYSLKLNNLGRFWMLRGNHECKHLTSYFTFKNE 194

  Fly   206 CIIKYSESIYDACMEAFDCLPLAALLNQQFLCIHGGLSPEIFTLDDIKTLNRFREPPAYGPMCDL 270
            .:.||...:||||..:|:.||||||:|.|:.|:|||:|||:.:::|:..:|||||.|:.|.||||
Yeast   195 MLHKYDMEVYDACCRSFNVLPLAALMNGQYFCVHGGISPELKSVEDVNKINRFREIPSRGLMCDL 259

  Fly   271 LWSDPLEDF-----GNE--KTNEFFSHNSVRGCSYFFSYSACCEFLQKNNLLSIVRAHEAQDAGY 328
            ||:||:|::     |:|  ::.:.|..||:||||:.|::.|.|:||:.|.||||:||||||||||
Yeast   260 LWADPVENYDDARDGSEFDQSEDEFVPNSLRGCSFAFTFKASCKFLKANGLLSIIRAHEAQDAGY 324

  Fly   329 RMYRKNQVTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWS 393
            |||:.|:|||||||||:||||||||.|:|||||||||.||||||||:.||||||||:||||||||
Yeast   325 RMYKNNKVTGFPSLITMFSAPNYLDTYHNKAAVLKYEENVMNIRQFHMSPHPYWLPDFMDVFTWS 389

  Fly   394 LPFVGEKVTEMLVNILNICSDDELVAGPDDELEEELRKKIVLVPANASNNNNNNNTPSKPASMSA 458
            |||||||||.|||:||||||:.||    |.|.|.:..::.|...|||:   ....|||...:.||
Yeast   390 LPFVGEKVTSMLVSILNICSEQEL----DPESEPKAAEETVKARANAT---KETGTPSDEKASSA 447

  Fly   459 L-----RKEIIRNKIRAIGKMSRVFSILREESESVLQLKGLTPTGALPVGALSGGRDSLKEALQG 518
            :     |::.:||||.||.|:||:||:||||||.|..||.:. .|.||.|||:.|.:.|.|.|.
Yeast   448 ILEDETRRKALRNKILAIAKVSRMFSVLREESEKVEYLKTMN-AGVLPRGALARGTEGLNETLS- 510

  Fly   519 LTASSHIHSFAEAKGLDAVNERMPP 543
                    :|.:|:..|.:||::||
Yeast   511 --------TFEKARKEDLINEKLPP 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CanA1	NP_524600.3	MPP_PP2B	81..385	CDD:277361	186/310 (60%)
CNA1	NP_013537.1	MPP_PP2B	70..381	CDD:277361	186/310 (60%)