Protein Alignment CanA1 and PPP6C

DIOPT Version :9

• Sequence 1: NP_001247378.2
• Gene: CanA1 / 43670
• FlyBaseID: FBgn0010015
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001116827.1
• Gene: PPP6C / 5537
• HGNCID: 9323
• Length: 342
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 128/317 - (40%)
• Similarity: 176/317 - (55%)
• Gaps: 40/317 - (12%)

  Fly    81 PNFDALRQHFLLEGRIEEAVALRIITEGAALLREEKNMIDVEAPITVCGDIHGQFFDLVKLFEVG 145
            |.|..||  ||.|         |:......||.||.|:..|..|:||||||||||:||.:||..|
Human    52 PVFHFLR--FLKE---------RLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTG 105

  Fly   146 GPPATTRYLFLGDYVDRGYFSIECVLYLWSLKITYPTTLSLLRGNHECRHLTEYFTFKQECIIKY 210
            |....|.|:|:||:|||||:|:|...||.:||..:|..::|||||||.|.:|:.:.|..||..||
Human   106 GQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKY 170

  Fly   211 -SESIYDACMEAFDCLPLAALLNQQFLCIHGGLSPEIFTLDDIKTLNRFREPPAYGPMCDLLWSD 274
             :.:.:..|.:.||.|.:|||:::|.||:||||||:|.|||.|:|:.|.:|.|..|..|||:|||
Human   171 GNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 235

  Fly   275 PLEDFGNEKTNEFFSHNSVRGCSYFFSYSACCEFLQKNNLLSIVRAHEAQDAGYR-MYRKNQVTG 338
            | ||......       |.||..:.|......||:..|||..|.|||:....||: |:.:
Human   236 P-EDVDTWAI-------SPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDE----- 287

  Fly   339 FPSLITIFSAPNYLDVYNNKAAVLKYEN-NVMNIRQFNCSPH-----------PYWL 383
              .|:|::|||||.....|.|:::.::: |....:.|...|.           ||:|
Human   288 --KLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIPPRTTTPYFL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CanA1	NP_001247378.2	MPP_PP2B	81..385	CDD:277361	128/317 (40%)
		PP2Ac	98..369	CDD:197547	116/273 (42%)
PPP6C	NP_001116827.1	MPP_PP2A_PP4_PP6	5..326	CDD:277360	124/299 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820