Protein Alignment CanA1 and PPP5C

DIOPT Version :9

• Sequence 1: NP_001247378.2
• Gene: CanA1 / 43670
• FlyBaseID: FBgn0010015
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_016882424.1
• Gene: PPP5C / 5536
• HGNCID: 9322
• Length: 551
• Species: Homo sapiens
• Alignment Length: 425
• Identity: 140/425 - (32%)
• Similarity: 210/425 - (49%)
• Gaps: 48/425 - (11%)

  Fly     1 MSATSTRSSVTRKSSLSKSSSSDKSAKSSSNSSKSPTAASGNKQKMQYTKTRERMVDDVPLPPTH 65
            |:....|:::....::.|....||.||...............::.:...:.:..:||.:.:   .
Human   107 MALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDI---E 168

  Fly    66 KLTMSEVYDDPK--TGKPNFD---ALRQHFLLEGRIEEAVALRIITEGAALLREEKNMIDV---- 121
            .:|:.:.|..||  .||....   .|.|.:..:.::....|.:|:.:...:|.:...:::.
Human   169 SMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKE 233

  Fly   122 EAPITVCGDIHGQFFDLVKLFEVGGPPATTR-YLFLGDYVDRGYFSIECVLYLWSLKITYPTTLS 185
            ...||||||.||||:||:.:||:.|.|:.|. |:|.||:||||.||:|.:|.|:..|:.||....
Human   234 TEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFH 298

  Fly   186 LLRGNHECRHLTEYFTFKQECIIKYSESIYDACMEAFDCLPLAALLNQQFLCIHGGL-SPEIFTL 249
            |||||||..::.:.:.|:.|...||:..:|:...|.|:.||||..:|.:.|.:|||| |.:..||
Human   299 LLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTL 363

  Fly   250 DDIKTLNRFREPPAYGPMCDLLWSDPLEDFGNEKTNEFFSHNSVRGCSYFFSYSACCEFLQKNNL 314
            |||:.:.|.|:||..|||||||||||....|..        .|.||.|..|.......||::|||
Human   364 DDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRS--------ISKRGVSCQFGPDVTKAFLEENNL 420

  Fly   315 LSIVRAHEAQDAGYRMYRKNQVTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVM--NIRQFNC- 376
            ..|:|:||.:..||      :|......:|:||||||.|...|||:.:..:.:.:  ...||..
Human   421 DYIIRSHEVKAEGY------EVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAV 479

  Fly   377 -----SPHPYWLPNFMDVFTWSLPFVGEKVTEMLV 406
                 .|.|  ||        |.|  |:|..|.||
Human   480 VSHPSGPLP--LP--------SRP--GDKEAETLV 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CanA1	NP_001247378.2	MPP_PP2B	81..385	CDD:277361	117/320 (37%)
		PP2Ac	98..369	CDD:197547	110/276 (40%)
PPP5C	XP_016882424.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900