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Protein Alignment CanA1 and PPP3CB

DIOPT Version :9

Sequence 1:	NP_001247378.2	Gene:	CanA1 / 43670	FlyBaseID:	FBgn0010015	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_001135825.1	Gene:	PPP3CB / 5532	HGNCID:	9315	Length:	525	Species:	Homo sapiens

Alignment Length:	528	Identity:	367/528 - (69%)
Similarity:	418/528 - (79%)	Gaps:	39/528 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 ERMVDDVPLPPTHKLTMSEVYDDPKTGKPNFDALRQHFLLEGRIEEAVALRIITEGAALLREEKN 117
            :|:|..||.||||:||..||:|  ..|.|..|.|:.|.:.|||::|.:|||||.||||:||.||.
Human    24 DRVVKAVPFPPTHRLTSEEVFD--LDGIPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKT 86

  Fly   118 MIDVEAPITVCGDIHGQFFDLVKLFEVGGPPATTRYLFLGDYVDRGYFSIECVLYLWSLKITYPT 182
            ||:||||||||||||||||||:|||||||.||.||||||||||||||||||||||||.|||.||:
Human    87 MIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPS 151

  Fly   183 TLSLLRGNHECRHLTEYFTFKQECIIKYSESIYDACMEAFDCLPLAALLNQQFLCIHGGLSPEIF 247
            ||.|||||||||||||||||||||.|||||.:|:|||||||.|||||||||||||:||||||||.
Human   152 TLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIH 216

  Fly   248 TLDDIKTLNRFREPPAYGPMCDLLWSDPLEDFGNEKTNEFFSHNSVRGCSYFFSYSACCEFLQKN 312
            |||||:.|:||:||||:|||||||||||.|||||||:.|.||||:|||||||::|.|.|||||.|
Human   217 TLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNN 281

  Fly   313 NLLSIVRAHEAQDAGYRMYRKNQVTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 377
            |||||:|||||||||||||||:|.|||||||||||||||||||||||||||||||||||||||||
Human   282 NLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 346

  Fly   378 PHPYWLPNFMDVFTWSLPFVGEKVTEMLVNILNICSDDELVAGPDDELEEELRKKIVLVPANASN 442
            ||||||||||||||||||||||||||||||:|:|||||||:...:|:.:
Human   347 PHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFD---------------- 395

  Fly   443 NNNNNNTPSKPASMSALRKEIIRNKIRAIGKMSRVFSILREESESVLQLKGLTPTGALPVGALSG 507
                       ...:|.|||||||||||||||:||||:|||||||||.||||||||.||.|.|:|
Human   396 -----------VGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAG 449

  Fly   508 GRDSL----------KEALQGLTASSHIHSFAEAKGLDAVNERMPPRRPLLMSASSSSITTVTRS 562
            ||.:|          ::|::|.:....|.||.||||||.:|||||||:..:.....:|:.|...:
Human   450 GRQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHAT 514

  Fly   563 SSSSSNNN 570
            .:..:.|:
Human   515 ENHGTGNH 522

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.