Protein Alignment CanA1 and PPP2CB

DIOPT Version :10

• Sequence 1: NP_524600.3
• Gene: CanA1 / 43670
• FlyBaseID: FBgn0010015
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001009552.1
• Gene: PPP2CB / 5516
• HGNCID: 9300
• Length: 309
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 121/280 - (43%)
• Similarity: 169/280 - (60%)
• Gaps: 17/280 - (6%)

  Fly   102 LRIITEGA-ALLREEKNMIDVEAPITVCGDIHGQFFDLVKLFEVGGPPATTRYLFLGDYVDRGYF 165
            :|.:.|.| .:|.:|.|:.:|..|:|||||:||||.||::||.:||....|.|||:||||||||:
Human    28 VRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYY 92

  Fly   166 SIECVLYLWSLKITYPTTLSLLRGNHECRHLTEYFTFKQECIIKY-SESIYDACMEAFDCLPLAA 229
            |:|.|..|.:||:.||..:::||||||.|.:|:.:.|..||:.|| :.:::....:.||.|||.|
Human    93 SVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTA 157

  Fly   230 LLNQQFLCIHGGLSPEIFTLDDIKTLNRFREPPAYGPMCDLLWSDPLEDFGNEKTNEFFSHNSVR 294
            |::.|..|:||||||.|.|||.|:.|:|.:|.|..||||||||||| :|.|....       |.|
Human   158 LVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDP-DDRGGWGI-------SPR 214

  Fly   295 GCSYFFSYSACCEFLQKNNLLSIVRAHEAQDAGYRMYRKNQVTGFPSLITIFSAPNYLDVYNNKA 359
            |..|.|.......|...|.|..:.|||:....||.......|      :||||||||.....|:|
Human   215 GAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNV------VTIFSAPNYCYRCGNQA 273

  Fly   360 AVLKYENNV-MNIRQFNCSP 378
            |:::.::.: .:..||:.:|
Human   274 AIMELDDTLKYSFLQFDPAP 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CanA1	NP_524600.3	MPP_PP2B	81..385	CDD:277361	121/280 (43%)
PPP2CB	NP_001009552.1	MPP_PP2A_PP4_PP6	9..293	CDD:277360	120/278 (43%)