Protein Alignment CanA1 and PPP1CA

DIOPT Version :9

• Sequence 1: NP_001247378.2
• Gene: CanA1 / 43670
• FlyBaseID: FBgn0010015
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001008709.1
• Gene: PPP1CA / 5499
• HGNCID: 9281
• Length: 341
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 117/325 - (36%)
• Similarity: 176/325 - (54%)
• Gaps: 54/325 - (16%)

  Fly    80 KPNFDALRQHFLLEGRIEEAVALRIITEGAALL---REEKN------------------------ 117
            |.|.|::... ||||.       |::|...|.:   |..||
Human     6 KLNLDSIIGR-LLEGS-------RVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPI 62

  Fly   118 MIDVEAPITVCGDIHGQFFDLVKLFEVGGPPATTRYLFLGDYVDRGYFSIECVLYLWSLKITYPT 182
            ::::|||:.:|||||||::||::|||.||.|..:.|||||||||||..|:|.:..|.:.||.||.
Human    63 LLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPE 127

  Fly   183 TLSLLRGNHECRHLTEYFTFKQECIIKYSESIYDACMEAFDCLPLAALLNQQFLCIHGGLSPEIF 247
            ...||||||||..:...:.|..||..:|:..::....:.|:|||:||:::::..|.||||||::.
Human   128 NFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 192

  Fly   248 TLDDIKTLNRFREPPAYGPMCDLLWSDPLEDFGNEKTNEFFSHNSVRGCSYFFSYSACCEFLQKN 312
            :::.|:.:.|..:.|..|.:||||||||.:|......|:       ||.|:.|......:||.|:
Human   193 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGEND-------RGVSFTFGAEVVAKFLHKH 250

  Fly   313 NLLSIVRAHEAQDAGYRMYRKNQVTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 377
            :|..|.|||:..:.||..:.|.|      |:|:||||||...::|..|::..:..:|      ||
Human   251 DLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM------CS 303

  Fly   378  377
            Human   304  303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CanA1	NP_001247378.2	MPP_PP2B	81..385	CDD:277361	116/324 (36%)
		PP2Ac	98..369	CDD:197547	107/297 (36%)
PPP1CA	NP_001008709.1	PTZ00480	6..319	CDD:185658	117/325 (36%)
		MPP_PP1_PPKL	8..309	CDD:277359	116/323 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820