DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CanA1 and Ppp1ca

DIOPT Version :9

Sequence 1:	NP_001247378.2	Gene:	CanA1 / 43670	FlyBaseID:	FBgn0010015	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_114074.1	Gene:	Ppp1ca / 19045	MGIID:	103016	Length:	330	Species:	Mus musculus

Alignment Length:	260	Identity:	104/260 - (40%)
Similarity:	158/260 - (60%)	Gaps:	19/260 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 MIDVEAPITVCGDIHGQFFDLVKLFEVGGPPATTRYLFLGDYVDRGYFSIECVLYLWSLKITYPT 182
            ::::|||:.:|||||||::||::|||.||.|..:.|||||||||||..|:|.:..|.:.||.||.
Mouse    52 LLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPE 116

  Fly   183 TLSLLRGNHECRHLTEYFTFKQECIIKYSESIYDACMEAFDCLPLAALLNQQFLCIHGGLSPEIF 247
            ...||||||||..:...:.|..||..:|:..::....:.|:|||:||:::::..|.||||||::.
Mouse   117 NFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 181

  Fly   248 TLDDIKTLNRFREPPAYGPMCDLLWSDPLEDFGNEKTNEFFSHNSVRGCSYFFSYSACCEFLQKN 312
            :::.|:.:.|..:.|..|.:||||||||.:|......|:       ||.|:.|......:||.|:
Mouse   182 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGEND-------RGVSFTFGAEVVAKFLHKH 239

  Fly   313 NLLSIVRAHEAQDAGYRMYRKNQVTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 377
            :|..|.|||:..:.||..:.|.|      |:|:||||||...::|..|::..:..:|      ||
Mouse   240 DLDLICRAHQVVEDGYEFFAKRQ------LVTLFSAPNYCGEFDNAGAMMSVDETLM------CS 292

Fly 378 377
Mouse 293 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CanA1	NP_001247378.2	MPP_PP2B	81..385	CDD:277361	104/260 (40%)
CanA1	NP_001247378.2	PP2Ac	98..369	CDD:197547	101/250 (40%)
Ppp1ca	NP_114074.1	PTZ00480	6..308	CDD:185658	104/260 (40%)
		MPP_PP1_PPKL	8..298	CDD:277359	104/260 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820