Protein Alignment 5-HT7 and htr1ab

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001139238.1
• Gene: htr1ab / 797538
• ZFINID: ZDB-GENE-090409-2
• Length: 403
• Species: Danio rerio
• Alignment Length: 416
• Identity: 163/416 - (39%)
• Similarity: 232/416 - (55%)
• Gaps: 52/416 - (12%)

  Fly   141 SDTPLLLE-----EFAAGEFVLP---PLT-SIFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRP 196
            :||..|.:     :.......||   ||: .|..|:::..:||.::.||..|..|:.:.|.|:..
Zfish     5 NDTSFLFQNDSDLDHQTDNVTLPVKVPLSYQISTSLLIGALILCSIFGNACVVAAIALERSLQNV 69

  Fly   197 CNYLLVSLALSDLCVALLVMPMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRY 261
            .|||:.|||::||.|::||:|||.||:||:||..|.:.|||::|.|:||||:|||:||||::|||
Zfish    70 ANYLIGSLAVTDLMVSVLVLPMAALYQVLDKWTLGQVTCDIFISLDILCCTSSILHLCAIALDRY 134

  Fly   262 LAITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLLILGNEHEDEEGQP-ICTVCQNFAYQIY 325
            .|||.|::|..|||.:|..|.:.:.|.....||:||:||:       :.|| .|.:..:..|.||
Zfish   135 WAITDPIDYMKKRTLKRAALLITVTWFVGFSISIPPMLIM-------KSQPKTCMISHDPWYTIY 192

  Fly   326 ATLGSFYIPLSVMLFVYYQIFRAARRIVL------EEKRAQ-----THLQQALNGTGS---PSAP 376
            :|..:|||||.:||.:|.:||:|||..:.      |:||.:     ..|.:..||..|   .||.
Zfish   193 STFCAFYIPLILMLVLYGRIFKAARFRIRKTVRKPEKKRVKCLTVSPALFKRANGELSKNWKSAV 257

  Fly   377 QAPPLGHTELASSGNGQ-RHSSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHK 440
            :..|      |:..||. :|:..|. ||........|.....|.      ....|..|..:.|.|
Zfish   258 EPKP------AACVNGAIKHAEDGE-SLEIIEVHSNSKNNLPLP------NTPNSVPLFENKHEK 309

  Fly   441 ----KLRFQLAKEKKASTTLGIIMSAFTVCWLPFFILALIRPF-ETMHVPASLSSLFLWLGYANS 500
                |.:..||:|:|...||||||..|.:|||||||.||:.|| .|..:|..|..:..||||:||
Zfish   310 NTEAKRKLALARERKTVKTLGIIMGTFILCWLPFFIKALVMPFCPTCVMPLWLQDVINWLGYSNS 374

  Fly   501 LLNPIIYATLNRDFRKPFQEILYFRC 526
            ||||||||..|:||:..|::|:  :|
Zfish   375 LLNPIIYAYFNKDFQSAFKKII--KC 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	79/169 (47%)
		7tm_1	179..507	CDD:278431	143/348 (41%)
htr1ab	NP_001139238.1	7tm_4	46..>208	CDD:304433	79/168 (47%)
		7tm_1	52..381	CDD:278431	143/348 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002041
OrthoInspector	1	1.000	-	-		otm24861
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910