Protein Alignment 5-HT7 and taar10d

DIOPT Version :10

• Sequence 1: NP_524599.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001076371.1
• Gene: taar10d / 794512
• ZFINID: ZDB-GENE-041014-97
• Length: 336
• Species: Danio rerio
• Alignment Length: 405
• Identity: 132/405 - (32%)
• Similarity: 177/405 - (43%)
• Gaps: 96/405 - (23%)

  Fly   142 DTPLLLEEF---AAGEFVLPPLTSIFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVS 203
            |.|.|..||   :..:||....|.|...|:|....:.|::||:||.|.|...|:|..|.|||::|
Zfish    14 DKPFLCYEFSNRSCQKFVYSLETRILFYILLSASSIITIIGNLLVIITVVHFRQLHTPTNYLILS 78

  Fly   204 LALSDLCVALLVMPMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPL 268
            ||::||.|..:|||.::|..:...|..|.|.|.|..|.||..|||||||||.||:|||.||..|.
Zfish    79 LAVADLLVGGVVMPPSMLRSIETCWYLGDLFCKIHSSLDVTLCTASILNLCIISLDRYYAICHPF 143

  Fly   269 EYGVKRTPRRMMLCVGIVWLAAACIS----LPPLLILGNE---HEDEEGQPICTVCQNFAYQIYA 326
            :|..|.|....::.:.|.|..:|.:.    ...|.|||.|   :|:.:....||:.|:.......
Zfish   144 QYHSKMTSLATLVMIIICWTVSAVLGFGMIFMELNILGVEDFYYENIKCDGGCTLFQSKTGGTVF 208

  Fly   327 TLGSFYIPLSVMLFVYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELASSGN 391
            :|..||||..|:||||.:|...|:|.|           ||:....|
Zfish   209 SLICFYIPALVILFVYLKILHEAQRQV-----------QAIQSVNS------------------- 243

  Fly   392 GQRHSSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEKKASTTL 456
                                                                 :|.||.||:.||
Zfish   244 -----------------------------------------------------ELKKEGKANKTL 255

  Fly   457 GIIMSAFTVCWLPFFILALIRPFETMHVPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQEI 521
            .||:..|...|:|||:..||.||....||..|..||.|:||.||..|||:||.....||..|:.|
Zfish   256 AIIIGVFLTLWVPFFLCNLIDPFIGYSVPPLLFDLFYWIGYYNSTCNPIVYAFFYSWFRHAFRVI 320

  Fly   522 L---YFRCSSLNTMM 533
            |   .|:.:|..|::
Zfish   321 LSKAIFQTNSSRTVL 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_524599.1	7tmA_5-HT7	163..518	CDD:320452	118/361 (33%)
		TM helix 1	164..190	CDD:320452	9/25 (36%)
		TM helix 2	197..223	CDD:320452	13/25 (52%)
		TM helix 3	235..265	CDD:320452	20/29 (69%)
		TM helix 4	277..299	CDD:320452	3/25 (12%)
		TM helix 5	319..348	CDD:320452	11/28 (39%)
		TM helix 6	447..477	CDD:320452	14/29 (48%)
		TM helix 7	486..511	CDD:320452	13/24 (54%)
taar10d	NP_001076371.1	7tmA_TAAR1	38..317	CDD:320438	118/361 (33%)
		TM helix 1	39..65	CDD:320438	9/25 (36%)
		TM helix 2	72..98	CDD:320438	13/25 (52%)
		TM helix 3	110..140	CDD:320438	20/29 (69%)
		TM helix 4	152..175	CDD:320438	3/22 (14%)
		TM helix 5	201..230	CDD:320438	11/28 (39%)
		TM helix 6	246..276	CDD:320438	14/29 (48%)
		TM helix 7	285..310	CDD:320438	13/24 (54%)