Protein Alignment 5-HT7 and htr6

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_009295353.1
• Gene: htr6 / 568269
• ZFINID: ZDB-GENE-030131-7839
• Length: 488
• Species: Danio rerio
• Alignment Length: 427
• Identity: 139/427 - (32%)
• Similarity: 186/427 - (43%)
• Gaps: 83/427 - (19%)

  Fly   165 VSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLVMPMALLYEVLEKWN 229
            ::::|.::||.|..||:|:...|...|.||...|..||||.||||.|||:|||.|:|..:...|.
Zfish    60 LAVMLSLIILVTACGNILLIALVFAHRSLRCTSNCFLVSLFLSDLMVALVVMPPAMLNVLCGTWV 124

  Fly   230 FGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAACIS 294
            ..|..|.:|:.|||:||:|||||||.||:||||.|..||.|....||.|.:|.||..|..||..|
Zfish   125 LAPGFCPVWLCFDVMCCSASILNLCVISLDRYLLIISPLRYKQHMTPPRALLLVGGAWGLAALTS 189

  Fly   295 LPPLLI----LGNEHEDEEGQP-------------------------ICTVCQNFAYQIYATLGS 330
            ..|:.:    ||...|..|..|                         .|.:.....:.:.||..:
Zfish   190 FLPIKMDWHSLGRMQELTEDDPGNATHLNSFYPSSYFQLSSSGMPSTQCRLRVTLPFALVATFLT 254

  Fly   331 FYIPLSVMLFVYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELASSGNGQRH 395
            |::|.:.:.|.|.:|..|||| ...:..|.||.....:..|.||.|.:|  ||.  ...|:...|
Zfish   255 FFLPSTAICFTYCRILLAARR-QARQVEALTHPAYPQHSLGEPSRPPSP--GHA--IQDGDDYSH 314

  Fly   396 SSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEK-----KASTT 455
            ..                                ..||..:|.......:||..:     |||.|
Zfish   315 QE--------------------------------PPGLRHAPLSVNSERRLAHRQRKRALKASLT 347

  Fly   456 LGIIMSAFTVCWLPFFILALIRPFETMHVPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQE 520
            ||:::..|...||||||..:.:.. ...||.|......||||.||.:|||||....|||::....
Zfish   348 LGVLLGLFFSAWLPFFITNMAQAV-CECVPPSFFDAITWLGYCNSTMNPIIYPMFMRDFKRALAR 411

  Fly   521 ILYFRCSS----------LNTMMRENYYQDQYGEPPS 547
            :|.. |||          |:..:|.:.......||||
Zfish   412 LLPC-CSSSQAPRRPSLPLSLSLRNSGEPQLPSEPPS 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	75/197 (38%)
		7tm_1	179..507	CDD:278431	120/361 (33%)
htr6	XP_009295353.1	7tm_1	74..398	CDD:278431	120/361 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910