Protein Alignment 5-HT7 and htr1b

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001122181.1
• Gene: htr1b / 561647
• ZFINID: ZDB-GENE-081022-141
• Length: 380
• Species: Danio rerio
• Alignment Length: 408
• Identity: 156/408 - (38%)
• Similarity: 224/408 - (54%)
• Gaps: 52/408 - (12%)

  Fly   125 ITSSNLGDSNTTLVPLSDTPLLLEEFAAGEFVLPPLTSIFVSIVLLIVILGTVVGNVLVCIAVCM 189
            :.:|:.| :|.||.|.:|..  .|.||         ..:.:|.||.::.|.|::.|..|...:..
Zfish    16 VLNSSTG-TNVTLTPKTDEK--QESFA---------FQVTLSSVLGLITLATILSNAFVIATISQ 68

  Fly   190 VRKLRRPCNYLLVSLALSDLCVALLVMPMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNLC 254
            .|||:.|.|:|:.|||::||.|::||||:.:||.|..:|..|.::||||:|.|:.|||||||:||
Zfish    69 SRKLQTPANFLIASLAVTDLLVSVLVMPICVLYTVTREWTLGQVICDIWLSSDITCCTASILHLC 133

  Fly   255 AISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLLILGNEHEDEEGQ-PICTV-C 317
            .|::|||.|||..:||..|||..|....|...|:.|..|||||..    ..:.:.|: ..|:| .
Zfish   134 VIALDRYWAITDAVEYAKKRTQARAAGMVATAWIIAISISLPPFF----WRQVKAGELTTCSVNT 194

  Fly   318 QNFAYQIYATLGSFYIPLSVMLFVYYQIFRAARRIVLEE--KRAQTHLQQALNGTGSPSAPQAPP 380
            .:..|.||:|.|:||||..:::.:|.:|:..||:.:|::  |:....|..|...|.||
Zfish   195 DHIFYTIYSTFGAFYIPTLLLIALYGRIYVEARKRILKQSPKKPGKRLTSAHLSTNSP------- 252

  Fly   381 LGHTELASSGNGQRHSSVGNTSLTYSTCG--GLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLR 443
                           :||.:||..:  ||  .|.|..|:| |..:...|:.|..||     :|.|
Zfish   253 ---------------ASVASTSPLH--CGRQDLCSDSGSL-GSDNQIRVTVSDSLL-----EKKR 294

  Fly   444 FQLAKEKKASTTLGIIMSAFTVCWLPFFILALIRPFETMHVPASLSSLFLWLGYANSLLNPIIYA 508
            ...|:|:||:.|||||:.|:.||||||||..|:.|..:......|...|.||||.|||:|||||.
Zfish   295 ISAARERKATKTLGIILGAYIVCWLPFFIYTLLIPLCSSCFSPELFDFFTWLGYVNSLINPIIYT 359

  Fly   509 TLNRDFRKPFQEILYFRC 526
            ..|.||:|.|.:::.|||
Zfish   360 MSNDDFKKAFHKVISFRC 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	73/170 (43%)
		7tm_1	179..507	CDD:278431	131/333 (39%)
htr1b	NP_001122181.1	7tm_1	59..358	CDD:278431	131/332 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24861
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3253
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.900