Protein Alignment 5-HT7 and htr1d

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001139158.1
• Gene: htr1d / 556429
• ZFINID: ZDB-GENE-090409-3
• Length: 386
• Species: Danio rerio
• Alignment Length: 410
• Identity: 154/410 - (37%)
• Similarity: 220/410 - (53%)
• Gaps: 58/410 - (14%)

  Fly   133 SNTTLVPLSDTPLLLEEFAAGEFVLPPLTSIFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPC 197
            |.|||....|..||             ...|.:|.:|.||.|.|.:.|..|...:.:.|||..|.
Zfish    18 SPTTLESWDDATLL-------------SLQISISAMLAIVTLATALSNAFVIATIFLTRKLHTPA 69

  Fly   198 NYLLVSLALSDLCVALLVMPMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYL 262
            |:|:.|||.:||.|::||||::::|.|.:.|..|.::||||:|.|:..||||||:||.|::|||.
Zfish    70 NFLIGSLAATDLLVSILVMPISIVYTVSKTWTLGQIVCDIWLSSDITFCTASILHLCVIALDRYW 134

  Fly   263 AITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLL-ILGNEHEDEEGQPICTVC----QNFAY 322
            |||..|||..:||.||..|.:.|||:.:..||||||. .....||:      .|.|    ...:|
Zfish   135 AITDALEYSKRRTMRRAALMIVIVWVISVSISLPPLFWRQAKAHEE------LTECMVNTDQISY 193

  Fly   323 QIYATLGSFYIPLSVMLFVYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELA 387
            .:|:|.|:||:|..:::.:|.:|:.|||..:.:        ..|.:|....:|         :|.
Zfish   194 TLYSTFGAFYVPTVLLMILYGRIYVAARSRIFK--------TPATSGKRFTAA---------QLI 241

  Fly   388 SSGNGQRHSSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKL--------RF 444
            .:..|....|:.:||   :..|.|::|||  .|.|.|||..|.:.|..:....||        |.
Zfish   242 QNSAGSSLCSLNSTS---NQEGHLNAGGG--GGSGGGGGGGGGSPLFTNSVKVKLADSVLERKRL 301

  Fly   445 QLAKEKKASTTLGIIMSAFTVCWLPFFILALIRPF--ETMHVPASLSSLFLWLGYANSLLNPIIY 507
            ..|:||||:.|||||:.||.|||||||:..|:...  :..:.|. |..:|.||||.|||:||:||
Zfish   302 CAAREKKATKTLGIILGAFIVCWLPFFVFTLVMGVCKDCWYHPV-LFDVFTWLGYLNSLINPVIY 365

  Fly   508 ATLNRDFRKPFQEILYF-RC 526
            ...|.||::.|.:::.| ||
Zfish   366 TAFNDDFKQAFHKLIKFKRC 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	73/173 (42%)
		7tm_1	179..507	CDD:278431	131/342 (38%)
htr1d	NP_001139158.1	7tm_1	52..365	CDD:278431	131/341 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm24861
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3253
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940