Protein Alignment 5-HT7 and Dop1R1

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001262563.1
• Gene: Dop1R1 / 41726
• FlyBaseID: FBgn0011582
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 512
• Identity: 156/512 - (30%)
• Similarity: 230/512 - (44%)
• Gaps: 105/512 - (20%)

  Fly    47 AYAAGKATVPAPLVEGETESATSQDFNSSSAFLGAIASASSTGSGSGSGSGSGSGSGSGSYGLAS 111
            |.|||..:|.|.:....|.|.      |||..:...:||::.|....|||...|.:.:    |..
  Fly    10 AIAAGVGSVAATVATSTTSSI------SSSTTIINTSSATTIGGNHTSGSTGFSTNST----LLD 64

  Fly   112 MNSSPIAIVS-----------------YQGIT-SSNLGDSNTTLVPLSDT-------PLLLEEFA 151
            .:..|:.:.:                 |.|.| :|...:|:.|.....||       ||.|
  Fly    65 ADHLPLQLTTAKVDLDIEIDIQLLTNGYDGTTLTSFYNESSWTNASEMDTIVGEEPEPLSL---- 125

  Fly   152 AGEFVLPPLTSIFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLVM 216
                    ::.:.|.|.|.::|..:|.||:|||:|:...|.|||..|..|.|||::||.||.|||
  Fly   126 --------VSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRRIGNLFLASLAIADLFVASLVM 182

  Fly   217 PMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMML 281
            ..|.:.::|..|.||...||.||:|||:|.|||||||||||:|||:.|..||.||...|.|..::
  Fly   183 TFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVI 247

  Fly   282 CVGIVWLAAACISLPPLLILGNEHEDE--------EGQPICTVCQNFAYQIYATLGSFYIPLSVM 338
            .:..:||.||.:|..| :.||....|:        :..|.|.:.....|.:.::..|||.|..||
  Fly   248 TIAAIWLLAAFVSFVP-ISLGIHRPDQPLIFEDNGKKYPTCALDLTPTYAVVSSCISFYFPCVVM 311

  Fly   339 LFVYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELASSGNGQRHSSVGNTSL 403
            :.:|.:::..|::.|...|        |:...|..:..|.    :..:....|..:...|.|..
  Fly   312 IGIYCRLYCYAQKHVKSIK--------AVTRPGEVAEKQR----YKSIRRPKNQPKKFKVRNLH- 363

  Fly   404 TYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEKKASTTLGIIMSAFTVCWL 468
            |:|                             ||:|       ..:.||:.|:|:||..|.:||:
  Fly   364 THS-----------------------------SPYH-------VSDHKAAVTVGVIMGVFLICWV 392

  Fly   469 PFFILALIRPFETMHVPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQEILYFR 525
            |||.:.:...|....:......:..||||:||..|||||:..|::||..|:.||..|
  Fly   393 PFFCVNITAAFCKTCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILTMR 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	76/176 (43%)
		7tm_1	179..507	CDD:278431	111/335 (33%)
Dop1R1	NP_001262563.1	7tm_4	134..>266	CDD:304433	65/132 (49%)
		7tm_1	145..431	CDD:278431	111/335 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010