Protein Alignment 5-HT7 and mAChR-B

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_649764.1
• Gene: mAChR-B / 40955
• FlyBaseID: FBgn0037546
• Length: 1019
• Species: Drosophila melanogaster
• Alignment Length: 440
• Identity: 109/440 - (24%)
• Similarity: 168/440 - (38%)
• Gaps: 147/440 - (33%)

  Fly    52 KATVPAPLVEGETESATSQDFNS----------------SSAFLGAIASASSTGSGSGSGSGSGS 100
            |..:.|..:.||     |.||||                ::..|.|:.:.||.|..:.|||.|.|
  Fly    59 KRLLEAAKIYGE-----SSDFNSWPVNEQLQWYRNFDVNNTNLLLAVRNQSSDGGSTMSGSSSDS 118

  Fly   101 GSGSGSYGLASMNSSPIAIVSYQGITSSNLGDSNTTLVPLSDTPLLLEEFAAGEFVLPPLT---S 162
                                              ..|.|                ||||..   :
  Fly   119 ----------------------------------EILGP----------------VLPPFALWQT 133

  Fly   163 IFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLVMPMALLYEVLEK 227
            |.::|.|.|.|:.||.||:||.:|..:.|.:|:|.||.:.|||.:|:.:..:.||...:|.:...
  Fly   134 ILIAICLAICIILTVGGNILVLLAFIVDRNIRQPSNYFIASLAATDMLIGTVSMPFYTIYVLKGY 198

  Fly   228 WNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAAC 292
            |:.||:|||:|:|.|...|..|...:..|::|||.::....:|...||..|::..|.|.|:
  Fly   199 WDLGPMLCDLWLSVDYTVCLVSQYTVLLITIDRYCSVKIAAKYRSWRTRTRVIYMVTITWI---- 259

  Fly   293 ISLPPLL----ILGNEHEDEE-----GQPICTVCQNFAYQIYAT---LGSFYIPLSVMLFVYYQI 345
              :|.||    |.|.||...:     ||  |.| |.....|:.|   :|.::..|.|:..:|..|
  Fly   260 --IPALLFFISIFGWEHFTGKRDLLPGQ--CAV-QFLKDPIFNTALIIGYYWTTLIVLFVLYAGI 319

  Fly   346 FRAARRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELASSGNGQRHSSVGNTSLTYSTCGG 410
            ::.|..:....:..|..:|                                     |:...:.|.
  Fly   320 YKTAYDMQKRSEAKQRKMQ-------------------------------------SMVALSAGA 347

  Fly   411 LSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEK----KASTTL 456
            :|    .:|||.:|.||.....|       |.:.:||.::    .|.||:
  Fly   348 MS----GMAGHAAGIGVIEEKIL-------KTKVELAGDQTDLDSACTTV 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	59/180 (33%)
		7tm_1	179..507	CDD:278431	77/294 (26%)
mAChR-B	NP_649764.1	7tm_1	150..>341	CDD:278431	62/236 (26%)
		7tm_4	150..>336	CDD:304433	60/194 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010