Protein Alignment 5-HT7 and adra2a

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_997520.3
• Gene: adra2a / 266750
• ZFINID: ZDB-GENE-021010-1
• Length: 388
• Species: Danio rerio
• Alignment Length: 393
• Identity: 134/393 - (34%)
• Similarity: 205/393 - (52%)
• Gaps: 47/393 - (11%)

  Fly   151 AAGEFVLPPLTSIFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLV 215
            |..|:.|  |.::.:|:.:.::||..:.|||||.|||...|.||.|.|..|||||.:|:.||.||
Zfish    13 ATKEYTL--LVALPLSVAVGLLILLIIFGNVLVIIAVFTSRALRAPQNLFLVSLASADILVATLV 75

  Fly   216 MPMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMM 280
            ||.:|..|::..|.||.:.|:|:::.|||.|||||.:|||||:|||.:||:.:||.:||||:|:.
Zfish    76 MPFSLANELMGMWTFGGVWCEIYLALDVLFCTASITHLCAISLDRYWSITQAIEYNLKRTPQRIK 140

  Fly   281 LCVGIVWLAAACISLPPLLILGNEHEDEEGQPICTVCQNFAYQIYATLGSFYIPLSVMLFVYYQI 345
            ..:.|||:.||.||.|||:.:.....|     ||.:.:...|.:.:.:|||::|..:|:.||.:|
Zfish   141 RIIFIVWIIAAVISCPPLITMKKSEGD-----ICDINKEKWYIVSSCIGSFFLPCIIMVLVYIRI 200

  Fly   346 FRAA-----------RRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELASSGNG------- 392
            ::.|           |:..:.:|....|  :.|||..:........:...::..|.:.
Zfish   201 YQIAKKRTRAPPGDHRKNEVGKKENDPH--EKLNGIQNAEPDDKDEINGVDMEESSSSDHKVSNP 263

  Fly   393 ---QRHSSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEKKAST 454
               ::.||.|.|.|:.     :..|.|            ..|....:....:.:.:..:||:.:.
Zfish   264 CSLKKKSSKGKTKLSQ-----IKPGDG------------DKTEACQTTKASRWKGRQNREKRFTF 311

  Fly   455 TLGIIMSAFTVCWLPFFILALIRPFETMHVPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQ 519
            .|.:::..|.:||.|||.......|....||.:|...|.|.||.||.||||||...|.|||:.|:
Zfish   312 VLAVVIGVFVICWFPFFFTYTFTAFCDCCVPETLFKFFFWFGYCNSSLNPIIYTIFNNDFRRSFK 376

  Fly   520 EIL 522
            :||
Zfish   377 KIL 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	78/168 (46%)
		7tm_1	179..507	CDD:278431	118/348 (34%)
adra2a	NP_997520.3	7tm_4	31..>165	CDD:304433	69/133 (52%)
		7tm_1	39..364	CDD:278431	118/348 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..291		15/101 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3253
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940