Protein Alignment 5-HT7 and Htr7

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001334371.1
• Gene: Htr7 / 15566
• MGIID: 99841
• Length: 470
• Species: Mus musculus
• Alignment Length: 378
• Identity: 149/378 - (39%)
• Similarity: 210/378 - (55%)
• Gaps: 62/378 - (16%)

  Fly   163 IFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLVMPMALLYEVL-E 226
            :.:..:|.::.|.|:.||.||.|:||.|:|||:|.|||:|||||:||.||:.|||...:.::: .
Mouse    85 VVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGG 149

  Fly   227 KWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAA 291
            ||.||...|:::::.||:||||||:.||.||:||||.||:||.|.|::..:.|...:..|||.:|
Mouse   150 KWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSA 214

  Fly   292 CISLPPLLILGNEHEDEEGQPICTVCQNFAYQIYATLGSFYIPLSVMLFVYYQIFRAARRIVLEE 356
            .|:||||........|::   :|.:.|:|.|.||:|..:||||:|||||:||||::|||:...:.
Mouse   215 SITLPPLFGWAQNVNDDK---VCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKH 276

  Fly   357 K-----RAQTHLQQALNGTGSPSAPQAPPLGHTELASSGNGQRHSSVGNTSLTYSTCGGLSSGGG 416
            |     |.|.....:|||                            |.........|..||.
Mouse   277 KFSGFPRVQPESVISLNG----------------------------VVKLQKEVEECANLSR--- 310

  Fly   417 ALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEKKASTTLGIIMSAFTVCWLPFFILALIRPF-- 479
                            ||  .|.:|......:|:||:||||||:.||||||||||:|:..|||
Mouse   311 ----------------LL--KHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFIC 357

  Fly   480 --ETMHVPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQEILYFRCSSLN 530
              ....:|..:....|||||||||:||.|||..|||.|..::.:|..:..::|
Mouse   358 GTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNIN 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	83/169 (49%)
		7tm_1	179..507	CDD:278431	137/337 (41%)
Htr7	NP_001334371.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849922
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20244
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106732
Panther	1	1.100	-	-	LDO	PTHR24247
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3253
SonicParanoid	1	1.000	-	-		X1464
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.870