Protein Alignment 5-HT7 and LOC1271887

DIOPT Version :10

• Sequence 1: NP_524599.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_310742.4
• Gene: LOC1271887 / 1271887
• VectorBaseID: AGAMI1_000352
• Length: 512
• Species: Anopheles gambiae
• Alignment Length: 410
• Identity: 100/410 - (24%)
• Similarity: 166/410 - (40%)
• Gaps: 121/410 - (29%)

  Fly   127 SSNLGDSNTTLVPLSDTPLLLEEFAAGEFVLPPLTSIFVSI--VLLIVILGTVVGNVLVCIAVCM 189
            :::...|:::::|..|...::.:    :.|      |:::|  :|::.|..   ||:|..|||..
Mosquito     7 AASSSSSSSSIIPFVDRVNVIHK----DLV------IWIAIDGILMVCIFS---GNILTIIAVWY 58

  Fly   190 VRKLR-RPCNYLLVSLALSDLCVALLVMPMALLYEVLEKWNFGPLLCDIWVSFDVLCCTASILNL 253
            .|:|: ...|..::|||:||:.|. |.:|..|.:.:.........||.:.....::.|:.||.||
Mosquito    59 YRRLQWLISNLFVLSLAISDIFVG-LTLPYHLAFYMGVDLGRQKHLCLLRFFVLIIACSVSIWNL 122

  Fly   254 CAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLLILGNEHE-------DEEGQ 311
            .||:||||:||..||.|....|.|..:..:|..|..|..|:..||  :.|:.|       ||...
Mosquito   123 IAIAVDRYIAICYPLHYTRLMTKRTALTILGFGWCLAISIATIPL--IWNKWETAQECEFDELLH 185

  Fly   312 PICTVCQNFAYQIYATLGSFYIPLSVMLF-VYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPSA 375
            |         :.:...:...:..:.:.|| ||::|:|.|.:          |.:|
Mosquito   186 P---------WYVAGVITPIFSVVWLCLFVVYWRIWREASK----------HAKQ---------- 221

  Fly   376 PQAPPLGHTELASSGNGQRHSSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHK 440
                                                      |..||.....|.|
Mosquito   222 ------------------------------------------LRAHGGASERSSS---------- 234

  Fly   441 KLRFQLAKEKKASTTLGIIMSAFTVCWLPFFILALIRPFETMHVPASLSSLF---LWLGYANSLL 502
                    :.|:...:.:||..||.||:|:|::.|.:.|  ..|..|..:|:   ..|..|||::
Mosquito   235 --------DWKSVQVVLLIMGCFTFCWIPYFVVVLTQIF--AFVEDSSPTLYKAAFSLAMANSMM 289

  Fly   503 NPIIYATLNRDFRKPFQEIL 522
            ||||||..|..||..|:::|
Mosquito   290 NPIIYAWKNTHFRYAFKQLL 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_524599.1	7tmA_5-HT7	163..518	CDD:320452	94/368 (26%)
		TM helix 1	164..190	CDD:320452	9/27 (33%)
		TM helix 2	197..223	CDD:320452	10/25 (40%)
		TM helix 3	235..265	CDD:320452	13/29 (45%)
		TM helix 4	277..299	CDD:320452	6/21 (29%)
		TM helix 5	319..348	CDD:320452	5/29 (17%)
		TM helix 6	447..477	CDD:320452	10/29 (34%)
		TM helix 7	486..511	CDD:320452	12/27 (44%)
LOC1271887	XP_310742.4	None