Protein Alignment 5-HT7 and htr4

DIOPT Version :9

• Sequence 1: NP_001263131.1
• Gene: 5-HT7 / 43669
• FlyBaseID: FBgn0004573
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_009289337.1
• Gene: htr4 / 101882850
• ZFINID: ZDB-GENE-160114-31
• Length: 423
• Species: Danio rerio
• Alignment Length: 377
• Identity: 129/377 - (34%)
• Similarity: 182/377 - (48%)
• Gaps: 96/377 - (25%)

  Fly   164 FVSIVLLIVILGTVVGNVLVCIAVCMVRKLRR-PCNYLLVSLALSDLCVALLVMPMALLYEVLEK 227
            |:|:|:|:    :|:||:||.:|||..|:||: ..||.:||||.:||.|::||||...:..:.:.
Zfish    65 FLSLVMLM----SVLGNLLVMVAVCKDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELIHQN 125

  Fly   228 WNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAI-TKPLEYGVKRTPRRMMLCVGIVWLAAA 291
            |.:|...|.:..|.|||..|||||:||.||:|||.|| .:||.|..|.||.|:.|.:|..|:...
Zfish   126 WIYGETFCLVRTSLDVLLTTASILHLCCISLDRYYAICCQPLVYRNKMTPLRVTLMIGGCWIIPT 190

  Fly   292 CISLPPLL----------------ILGNEHEDEEGQPICTVCQNFAYQIYATLGSFYIPLSVMLF 340
            .||..|::                |.||       ..:|....|..|.:..::.:||:||.:|:.
Zfish   191 VISFLPIMQGWNSIGIKDLIDKRKISGN-------STVCVFMVNKPYALTCSVVAFYLPLVLMVL 248

  Fly   341 VYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELASSGNGQRHSSVGNTSLTY 405
            .|.:|:..||    |..|..:.||:| .|.|:              |.|.:.||
Zfish   249 AYQRIYVTAR----EHARQISMLQRA-GGAGN--------------ADSADHQR----------- 283

  Fly   406 STCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEKKASTTLGIIMSAFTVCWLPF 470
                                            :|:     :..|.||:.||.|||..|.:||.||
Zfish   284 --------------------------------NHR-----MRTETKAAKTLCIIMGCFCLCWAPF 311

  Fly   471 FILALIRPFETMHVPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQEIL 522
            ||..::.||....||..|.:..|||||.||:||||:||.||:.||:.|..||
Zfish   312 FITNVVDPFIDYSVPEQLWAACLWLGYINSMLNPILYAFLNKSFRRAFLIIL 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
5-HT7	NP_001263131.1	7tm_4	173..>342	CDD:304433	69/186 (37%)
		7tm_1	179..507	CDD:278431	115/345 (33%)
htr4	XP_009289337.1	7tm_4	68..>198	CDD:304433	60/133 (45%)
		7tm_1	76..348	CDD:278431	115/345 (33%)
		TAS2R	<172..365	CDD:283059	77/266 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910