DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ctr1C and slc31a2

DIOPT Version :9

Sequence 1:	NP_651837.1	Gene:	Ctr1C / 43668	FlyBaseID:	FBgn0062411	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_002937270.1	Gene:	slc31a2 / 733902	XenbaseID:	XB-GENE-5805083	Length:	175	Species:	Xenopus tropicalis

Alignment Length:	208	Identity:	54/208 - (25%)
Similarity:	93/208 - (44%)	Gaps:	60/208 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 MAMFFHTGDSETILFKFWRTESAMALTLSCLLIFMVAVLYEALKFFREWLFSWDRKRLAGGRDQY 127
            |.|:|...::.|:||.||..::...|.|||:::.::.||||..|.       | :..|.|...|
Frog     1 MQMYFVFSENVTLLFDFWTVQTLAGLILSCVVVLLLTVLYEVSKV-------W-KSNLLGQALQ- 56

  Fly   128 NRPRRYREANYNYNQPTYPPRTNQQSGTQVYAYRPRSPSMPPLQPPGRSSPQAQSSLIL------ 186
                            |:|.|:..:.          :||..|       .|:|.||::.
Frog    57 ----------------TFPIRSTHEP----------TPSSTP-------DPEASSSIVCDPLLPS 88

  Fly   187 TQHTHHHVQ-------ENTPPAGRTTKLKVFCSGMHILQTFLHVLQVLISFLLMLVFMTFNVWLC 244
            ...:|.||:       |.|.|:..:.     ...:|...:.||:.||::.::|||..|::|..:.
Frog    89 ASLSHQHVERLPPVIVERTQPSSNSR-----WWFLHSFLSLLHMSQVVLGYMLMLCVMSYNAAIF 148

  Fly   245 VAVLLGAGVGYYI 257
            :||:||:|:||::
Frog   149 IAVVLGSGLGYFL 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctr1C	NP_651837.1	SelP_N	<23..56	CDD:282453
Ctr1C	NP_651837.1	Ctr	63..258	CDD:282057	54/208 (26%)
slc31a2	XP_002937270.1	Ctr	3..161	CDD:367839	53/204 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1389393at2759
OrthoFinder	1	1.000	-	-		FOG0000938
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12483
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4018
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.140