DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ctr1C and ctr5

DIOPT Version :9

Sequence 1:	NP_651837.1	Gene:	Ctr1C / 43668	FlyBaseID:	FBgn0062411	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_594269.1	Gene:	ctr5 / 2542949	PomBaseID:	SPAC1142.05	Length:	173	Species:	Schizosaccharomyces pombe

Alignment Length:	205	Identity:	37/205 - (18%)
Similarity:	65/205 - (31%)	Gaps:	81/205 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 MSMAMFFHTGDSETILFKFWRTESAMALTLSCLLIFMVAVLYEAL----KFFREWLFSWDR-KRL 120
            |||...::..|| ..|.|.|...:......|.:.||..||..|.|    :.|..|:.:... |.|
pombe    29 MSMLWNWYIHDS-CFLAKSWHINTGNKFAGSIIGIFFFAVAIEGLSLVQRMFDRWIVAHSNGKTL 92

  Fly   121 AGGRDQYNRPRRYREANYNYNQPTYPPRTNQQSGTQVYAYRPRSPSMPPLQPPGRSSPQAQSSLI 185
            :|       |.|                          .:.|.|
pombe    93 SG-------PLR--------------------------IFFPSS--------------------- 103

  Fly   186 LTQHTHHHVQENTPPAGRTTKLKVFCSGMHILQTFLHVLQVLISFLLMLVFMTFNVWLCVAVLLG 250
                              |..:.|:   ..:::..::....|.:.:|||:.|:||.:..:...:|
pombe   104 ------------------TVHVTVW---QQLIRAAMYSSFYLSATILMLIVMSFNGYAILFGFVG 147

  Fly   251 AGVGYYIFCA 260
            |.:|:::|.:
pombe   148 AWIGFFLFAS 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctr1C	NP_651837.1	SelP_N	<23..56	CDD:282453
Ctr1C	NP_651837.1	Ctr	63..258	CDD:282057	34/199 (17%)
ctr5	NP_594269.1	Ctr	29..155	CDD:282057	36/201 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	42	1.000	Domainoid score	I3667
eggNOG	1	0.900	-	-		E1_KOG3386
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12483
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910