DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ctr1C and Slc31a2

DIOPT Version :9

Sequence 1:	NP_651837.1	Gene:	Ctr1C / 43668	FlyBaseID:	FBgn0062411	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_079562.1	Gene:	Slc31a2 / 20530	MGIID:	1333844	Length:	143	Species:	Mus musculus

Alignment Length:	196	Identity:	50/196 - (25%)
Similarity:	81/196 - (41%)	Gaps:	62/196 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 MAMFFHTGDSETILFKFWRTESAMALTLSCLLIFMVAVLYEALKFFREWLFSWDRKRLAGGRDQY 127
            |.|.|...|...:||.|||..|...:.||.|::.::|||||.:|..:..|.....:.|
Mouse     1 MPMHFIFSDEAVLLFDFWRVHSPTGMALSVLVVLLLAVLYEGIKVGKAKLLHKTLESL------- 58

  Fly   128 NRPRRYREANYNYNQPTYPPRTNQQSGTQVYAYRPRSPSMPPLQPPGRSSPQAQSSLILTQHTHH 192
                               |.||.|..               :..|.:.|..::|:
Mouse    59 -------------------PATNSQQF---------------ILGPDQDSTGSRST--------- 80

  Fly   193 HVQENTPPAGRTTKLKVF-CSGMHILQTFLHVLQVLISFLLMLVFMTFNVWLCVAVLLGAGVGYY 256
                    :...|:|:.| |   :..|:.:||:||:|.:.:||..|::|.|:.:.|:||:.||||
Mouse    81 --------SDNRTRLRWFLC---YFGQSLVHVIQVVIGYFVMLAVMSYNTWIFLGVVLGSAVGYY 134

  Fly   257 I 257
            :
Mouse   135 L 135

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctr1C	NP_651837.1	SelP_N	<23..56	CDD:282453
Ctr1C	NP_651837.1	Ctr	63..258	CDD:282057	50/196 (26%)
Slc31a2	NP_079562.1	Ctr	1..135	CDD:282057	49/194 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846126
Domainoid	1	1.000	91	1.000	Domainoid score	I7689
eggNOG	1	0.900	-	-		E1_KOG3386
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	92	1.000	Inparanoid score	I5076
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1389393at2759
OrthoFinder	1	1.000	-	-		FOG0000938
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12483
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4018
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.890