Protein Alignment Ptx1 and RHOXF2

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_115887.1
• Gene: RHOXF2 / 84528
• HGNCID: 30011
• Length: 288
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 68/233 - (29%)
• Similarity: 92/233 - (39%)
• Gaps: 51/233 - (21%)

  Fly   174 EKLR-IWAETGDFRDSHSSMTAVANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTE 237
            |||: ..|:.|:.:|..........:....||.......||.        .|||   .|.:.::|
Human    58 EKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGDLEGTSG--------SDGN---VEDSDQSE 111

  Fly   238 NISSSGHDEPM-TTSGEEPKNDKKNKRQRRQRTH-FTSQQLQELEHTFSRNRYPDMSTREEIAMW 300
            ......:..|. ...|.||.|      .::...| ||..||||||..|.|.::|....|..:|..
Human   112 KEPGQQYSRPQGAVGGLEPGN------AQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARS 170

  Fly   301 TNLTEARVRVWFKNRRAKWRKRERNAM------------------NAAVAAADFKSGFGTQFMQP 347
            .|:||..|::||:|||||||:.:|..|                  ..|:.|..|.||....:
Human   171 MNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDY--- 232

  Fly   348 FADDSLYSSYPYNNWTKVPSPLGTKPFPWPVNPLGSMV 385
            |.|.|..||..:      |.|    |||.|..||..|:
Human   233 FWDHSHSSSLCF------PMP----PFPPPSLPLPLML 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	26/56 (46%)
RHOXF2	NP_115887.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..136		20/94 (21%)
		Homeodomain	139..191	CDD:459649	26/51 (51%)
		PRK02287	<183..>232	CDD:235024	14/48 (29%)
		Nuclear localization signal. /evidence=ECO:0000250	186..195		5/8 (63%)