Protein Alignment Ptx1 and MIXL1

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001269331.1
• Gene: MIXL1 / 83881
• HGNCID: 13363
• Length: 240
• Species: Homo sapiens
• Alignment Length: 226
• Identity: 59/226 - (26%)
• Similarity: 86/226 - (38%)
• Gaps: 82/226 - (36%)

  Fly   264 QRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARV--------RVWFKNRRAKWR 320
            |||:||.|:::|||.||..|.|.||||:..||.:|..|.|.|:|:        :|||:|||||.|
Human    86 QRRKRTSFSAEQLQLLELVFRRTRYPDIHLRERLAALTLLPESRIQLLFSPLFQVWFQNRRAKSR 150

  Fly   321 KRERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSY--PYNNWTKVPSPLGTKPFPWPVNPLGS 383
            ::.                 |..| ||.|...:..::  | ...||...|    ..|..|:
Human   151 RQS-----------------GKSF-QPLARPEIILNHCAP-GTETKCLKP----QLPLEVD---- 188

  Fly   384 MVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCPYTTPANPYMYRS 448
                      |||...               |..:|..:|::|:.|.....|
Human   189 ----------VNCLPE---------------PNGVGGGISDSSSQGQNFETC------------- 215

  Fly   449 AAEPCMSSSMSSSIATLRLKAKQHASAGFGS 479
                   |.:|..|.:.....::|..:.||:
Human   216 -------SPLSEDIGSKLDSWEEHIFSAFGN 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	31/63 (49%)
MIXL1	NP_001269331.1	Homeodomain	87..151	CDD:459649	31/63 (49%)