Protein Alignment Ptx1 and uncx

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: XP_005164261.1
• Gene: uncx / 798510
• ZFINID: ZDB-GENE-080509-1
• Length: 483
• Species: Danio rerio
• Alignment Length: 542
• Identity: 122/542 - (22%)
• Similarity: 192/542 - (35%)
• Gaps: 147/542 - (27%)

  Fly   143 HHSAGQDLVGGYSQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSH--SSMTAVANSLDSTHLN 205
            |...|..| ||....|:|.       .|..:.:|.          .|  .|..||..|:|.. ||
Zfish    11 HAQFGGSL-GGMVSFPYHL-------SHHHVYELA----------GHQLQSTAAVPFSIDGL-LN 56

  Fly   206 NFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDE--PMTTSGEEPKNDKKNKRQRRQR 268
            .   |.|:|:             ||...:.:.....:|.::  .:|.|| :|..|....::||.|
Zfish    57 G---SCTASV-------------VNSNPLLSSGCGMNGDNQQYKLTDSG-DPDKDSPGCKRRRTR 104

  Fly   269 THFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRE-------RNA 326
            |:||..||:|||..|:.:.|||:..||.:|:..:|.|:||:|||:||||||||:|       |.|
Zfish   105 TNFTGWQLEELEKAFNESHYPDVFMREALALRLDLIESRVQVWFQNRRAKWRKKENTKKGPGRPA 169

  Fly   327 MNA-------------AVAAADF-------------------KSGFGTQFMQPFADDSLYSSYPY 359
            .|:             .:|..:.                   |...|..|..|.:|.....|...
Zfish   170 HNSHPTTCSGEPMDPEEIARRELERLEKKKRKQERRLLKSQNKLLPGDLFHTPGSDSDSGLSQIT 234

  Fly   360 NNWTKVPSPLGTKPFPWPVNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSN 424
            ::...:...:|                  .:|...:|..|...  ..:..||..  .:.||.| :
Zfish   235 DSEQSLHCDMG------------------RNQTQPSCDQTPQK--LQNQRNADQ--DASGSEL-D 276

  Fly   425 TSNVGAVGAPCPYTTPA-----NPYMYRSA---AEPCMSSSMSSSIATLR-LKAKQH-------A 473
            :|:.|.....|..:..:     ||:...|.   :.|.....|...:.|.| |..|.|       .
Zfish   277 SSDSGQQSNLCSNSRSSALQKLNPFSVESLLSDSRPRRKPPMDFPVPTPRPLIGKGHFLLYPITQ 341

  Fly   474 SAGFGSPY-----SAPSPVSRSNSAGLSACQYTGVGVTDVVXENALGALLNQHQHHLQHFSGGSV 533
            ..||..|.     :||.|.:.:...|         ..||:......|     |::..::.|..:.
Zfish   342 PLGFIVPQTALKSTAPGPDTENGQKG---------PATDITFAGNPG-----HRNAKENNSVNNN 392

  Fly   534 GGSGVPNGMQQHSGNMLHHSNLGLDHSDLGLVGGGPSNHQ----------DEGNHSLEGSNKSPM 588
            .|:....|....|||:...:......:.:.....|..|.:          |..:...|...:|..
Zfish   393 SGARAIKGQVSQSGNISCSTQSSSPQTTINGHSAGSCNERCPQDIELELVDPKSPQSEKKEQSLP 457

  Fly   589 EAPLANSSNNNNNDNDDEDVID 610
            :.|..||.:...:.:.|:|.:|
Zfish   458 DYPPQNSESATTSKDTDKDSVD 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	31/55 (56%)
uncx	XP_005164261.1	COG5576	<88..208	CDD:227863	42/120 (35%)
		Homeodomain	101..157	CDD:459649	31/55 (56%)