Protein Alignment Ptx1 and pb

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: XP_061500970.1
• Gene: pb / 5667717
• VectorBaseID: AGAMI1_011971
• Length: 790
• Species: Anopheles gambiae
• Alignment Length: 709
• Identity: 144/709 - (20%)
• Similarity: 224/709 - (31%)
• Gaps: 238/709 - (33%)

  Fly    46 NGLEAMSAESTGLCLQDLVSAGTANGA---GSA---GSAESATTTSTALSSGSTGSSTVNGGGSS 104
            |.||.|.|:        :.|...|.|:   |:|   ||....|.......:.:....|:..|.:.
Mosquito     6 NSLEHMGAQ--------IKSESPAIGSLHVGTAVVVGSETDITNAQQVSLTTNQQQQTIIAGSTQ 62

  Fly   105 TSGTEHLHSHHSLHDSSSSVSIS-PAISSLMPISSLSHLHHSAGQDLVGGYSQHPHHTVVPPHTP 168
            ..|.:.:     :.|.::.|:.. ..|:|:.|:.:     .:|.|       |.||
Mosquito    63 LIGRKQV-----ICDKTTRVATQLSVITSVEPLGA-----QAATQ-------QQPH--------- 101

  Fly   169 KHEPLEKLRIWA--ETGDFRDSHSSMTAVANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNE 231
            :.:.:.....|.  |:| |.:|..||......:||                            ..
Mosquito   102 QQQRIADTSYWMQNESG-FINSQPSMAEFLTHIDS----------------------------ES 137

  Fly   232 TTIKTENISSSGHDEPMTTSGEEP-KNDKKNKRQ--------------RRQRTHFTSQQLQELEH 281
            ..:.|:.| ..|..:.|.:..|.| ..:||..|:              ||.||.:|:.||.|||.
Mosquito   138 PKLVTQGI-PIGPSDNMESVPEYPWMKEKKTARKATAQAEFVAENGLPRRLRTAYTNTQLLELEK 201

  Fly   282 TFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAAVAAAD-------FKSG 339
            .|..|:|.....|.|||...:|||.:|:|||:|||.|.:::..:..:...:..|       .||.
Mosquito   202 EFHFNKYLCRPRRIEIAASLDLTERQVKVWFQNRRMKHKRQTLSKTDDDESGKDDLKDSNSKKSC 266

  Fly   340 FGTQFMQPFADDSLYSSYPYNNWT--KVPSPLGTKPFPWPVNPLGSMVAGNHHQNSVNCFNTGAS 402
            .|.:.......||..||...||.|  .|.:|..|.....|....||...|.   |:|:..::.||
Mosquito   267 QGCELPSDDIPDSTSSSRGMNNNTPNTVMTPNSTIDISTPTGGGGSTSGGT---NAVSADSSVAS 328

  Fly   403 -----------------GVAVSMNNASMLPGSMGSSLSNTSNVG------------AVGAPCP-- 436
                             ..|:...:.|....|..:|..:..|.|            :...|.|
Mosquito   329 TDSIDEEDDVHAKVKKKSDAIKKESVSSTKVSNSNSFKSYDNSGYPKDNGLISGPPSAAIPIPHS 393

  Fly   437 -----------------------------YTTPANPY---MYRSAAEPCMSSSMSSSIAT----- 464
                                         |..|.:.|   .::....|.:...:..|.||
Mosquito   394 PVSSSAISPTNNINSNNNNSNNNNNLQLYYNHPNHSYGVIKHKCPPGPVIGHEIEGSPATTGPSA 458

  Fly   465 --LRLKAKQ-----------HASAGF----------GSPYSAPSPVSRSNSAGLSACQYT----- 501
              :....||           |....:          |:.|:....:...:..|.....|.
Mosquito   459 GGIYFNNKQQEYFSKTECGLHYQPSYQHYQKTVVPPGAIYTNTQHILNDSYQGAQKIDYNPAQSL 523

  Fly   502 -GVGVTDVVXENALGALLNQHQHHLQHF------------------SGGSVGGSGVPNGMQQHSG 547
             |.....:| :|      :|..||.|..                  :|.:..|..||:|...:|.
Mosquito   524 KGFSTKPLVQDN------SQKLHHQQQMQNDPTFQSQNQPFYNSCDTGHNGAGQYVPSGQHYYSN 582

  Fly   548 NMLHHSNLG-----LDHSDLGLVGGGPSNHQDEG----NHSLEGSNKSPME----APLA 593
            :.......|     .:|:.:.|||   .||..:.    .|:...||.: ||    ||.|
Mosquito   583 DYDPQHEFGGGTGYYEHTKMSLVG---QNHYYDSMGSFQHNTVASNNN-MEYQGNAPYA 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	28/55 (51%)
pb	XP_061500970.1	None