Protein Alignment Ptx1 and PROP1

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_006252.4
• Gene: PROP1 / 5626
• HGNCID: 9455
• Length: 226
• Species: Homo sapiens
• Alignment Length: 210
• Identity: 65/210 - (30%)
• Similarity: 94/210 - (44%)
• Gaps: 52/210 - (24%)

  Fly   255 PKNDKKNK--RQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRA 317
            |:..::.:  .:||.||.|:..||::||..|.||:|||:..||.:|..|.|:|||::|||:||||
Human    58 PQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRA 122

  Fly   318 KWRKRERNAMN--AAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKPFPW---- 376
            |.||:||:.:.  |.::.|.|.|         |..:|....|.|   ...|.|:...|.|:
Human   123 KQRKQERSLLQPLAHLSPAAFSS---------FLPESTACPYSY---AAPPPPVTCFPHPYSHAL 175

  Fly   377 PVNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVG-APCPYTTP 440
            |..|                 :||.: .|:|..:....|         |.:....| .|||...|
Human   176 PSQP-----------------STGGA-FALSHQSEDWYP---------TLHPAPAGHLPCPPPPP 213

  Fly   441 ANPYMYRSAAEPCMS 455
            ..|.    :.||..|
Human   214 MLPL----SLEPSKS 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	31/55 (56%)
PROP1	NP_006252.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		4/16 (25%)
		Homeodomain	70..126	CDD:459649	31/55 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..226		11/42 (26%)