Protein Alignment Ptx1 and Dfd

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 700
• Identity: 136/700 - (19%)
• Similarity: 193/700 - (27%)
• Gaps: 321/700 - (45%)

  Fly    64 VSAGTANGAGSAGSAESATTTSTALSSGSTGSSTVNGGGSSTSGTEHLHS-------------HH 115
            ::|.|.:.:|:.|              |..|..:|.|||:. ..|.|.||             ||
  Fly    45 MTASTGHMSGAVG--------------GGAGVGSVGGGGAG-GMTGHPHSMHPADMVSDYMAHHH 94

  Fly   116 SLHDSSSSVSIS-PAISSLMPISSLSHLHHSAGQDLVGGYS---------QHPH-HTVVPPHTPK 169
            :.|..|.|.:.| |...|...||.    ||.|.   .||||         .||| |    ||...
  Fly    95 NPHSHSHSHTHSLPHHHSNSAISG----HHQAS---AGGYSSNYANATPPSHPHSH----PHAHP 148

  Fly   170 HEPL--------EKLRIWAETGDFRDSHSSMTAVAN----------------------------- 197
            |:.|        |.:...|...|..:.:.....|.|
  Fly   149 HQSLGYYVHHAPEFISAGAVHSDPTNGYGPAANVPNTSNGGGGGGSGAVLGGGAVGGSANGYYGG 213

  Fly   198 ----------SLDSTHLNN-----------FQTSSTSSISNRS---------------------- 219
                      |:.|||...           .|.|||...:|.:
  Fly   214 YGGGYGTANGSVGSTHSQGHSPHSQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQ 278

  Fly   220 -----------------------RDRKDGNRSVNE--TTIKTENISSSGHDEPM---TTSGE--- 253
                                   .||...:||.:|  :....:::..|..||.:   ||.||
  Fly   279 QLQELGMRLRCDDMGSENDDMSEEDRLMLDRSPDELGSNDNDDDLGDSDSDEDLMAETTDGERII 343

  Fly   254 ---------------------EPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEI 297
                                 |||         ||||.:|..|:.|||..|..|||.....|.||
  Fly   344 YPWMKKIHVAGVANGSYQPGMEPK---------RQRTAYTRHQILELEKEFHYNRYLTRRRRIEI 399

  Fly   298 AMWTNLTEARVRVWFKNRRAKWRKRER--NAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYN 360
            |....|:|.::::||:|||.||:|..:  |..|......|....
  Fly   400 AHTLVLSERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVDANGN--------------------- 443

  Fly   361 NWTKVPSPLGTKPFPWPVNPLGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNT 425
                 |:|:..||         :..|.:..|                 ..|.....|.......|
  Fly   444 -----PTPVAKKP---------TKRAASKKQ-----------------QQAQQQQQSQQQQTQQT 477

  Fly   426 SNVGAVGAPCPYTTPANPYMYRSAAEPCMSSSMSSSIATLRLKAKQHASAGFGS-PYSAPSPVSR 489
                             |.|     ..|:.|....||..:        |:..|: ||...:|.:.
  Fly   478 -----------------PVM-----NECIRSDSLESIGDV--------SSSLGNPPYIPAAPETT 512

  Fly   490 SNSAGLSACQYTGVGVTDVVXENALGALLNQHQHHLQHFSGGSVGGSGVPNGMQQHSGNMLHHSN 554
            |:..|..                             ||.|..:..|||..|....::.:.|:::|
  Fly   513 SSYPGSQ-----------------------------QHLSNNNNNGSGNNNNNNNNNNSNLNNNN 548

  Fly   555 LGLDHSDLGLVGGGPSNHQDEGNHSLEGSNKSPMEAPLANSSNNNNNDND 604
                            |:...|:.:|.|..:......:.|...:...|.|
  Fly   549 ----------------NNNQMGHTNLHGHLQQQQSDLMTNLQLHIKQDYD 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	26/55 (47%)
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	27/64 (42%)