Protein Alignment Ptx1 and pb

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_476669.3
• Gene: pb / 40826
• FlyBaseID: FBgn0051481
• Length: 782
• Species: Drosophila melanogaster
• Alignment Length: 710
• Identity: 157/710 - (22%)
• Similarity: 233/710 - (32%)
• Gaps: 250/710 - (35%)

  Fly     4 SSAVGGCGG----GGGLGVGVVTSSATALGPGGLTNGGGGVVSGALNGLEAMSAESTGLCLQDLV 64
            |..||||||    ||..||||      ::|..|:...|...|...|     |..:.|..|  |..
  Fly    34 SLPVGGCGGAGVVGGVGGVGV------SVGQPGIGQQGVPPVPSVL-----MVNKMTPNC--DKR 85

  Fly    65 SAGTANGAGSAGSAESATTTSTALSSGSTGSSTVNGGGSSTSGTEHLHSHHSLHDSSSSVSISPA 129
            ||.||             ...||...|     .:|...|......||...            ||.
  Fly    86 SADTA-------------YWMTASEGG-----FINSQPSMAEFLNHLSPE------------SPK 120

  Fly   130 ISSLMPISSLSHLHHSAGQDLVGGYSQHPHHTV---------VPPHTPKHEPLEKLRIWAETGDF 185
            |.:  |:          |...:||...:.:..|         |.|.||
  Fly   121 IGT--PV----------GSGAIGGVGVNVNVNVGVGVGYPVGVVPQTP----------------- 156

  Fly   186 RDSHSSMTAVANSLDST----HLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDE 246
                       :.:||.    .:...:||..||.:|     ..|:.|:.|..
  Fly   157 -----------DGMDSVPEYPWMKEKKTSRKSSNNN-----NQGDNSITEFV------------- 192

  Fly   247 PMTTSGEEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVW 311
                        .:|...||.||.:|:.||.|||..|..|:|.....|.|||...:|||.:|:||
  Fly   193 ------------PENGLPRRLRTAYTNTQLLELEKEFHFNKYLCRPRRIEIAASLDLTERQVKVW 245

  Fly   312 FKNRRAKWRKR---------ERNAMNAAVAAADF-----KSGFGTQFMQPFADDSLYSSYPYNNW 362
            |:|||.|.:::         .::::......:|.     ||..|.:.......||..:|..:||.
  Fly   246 FQNRRMKHKRQTLSKTDDEDNKDSLKGDDDQSDSNSNSKKSCQGCELPSDDIPDSTSNSRGHNNN 310

  Fly   363 TKVPSPLGTKPFPWPVNPLGSMVAGNHHQNSVNCFNTGAS-----GVAVSMNNASMLPGSMGSSL 422
            |  ||.....|           .|||...||  ...||.|     ...||.:|......|:.||:
  Fly   311 T--PSATNNNP-----------SAGNLTPNS--SLETGISSNLMGSTTVSASNVISADSSVASSV 360

  Fly   423 SNTSNV-------------------GAVGAPCPYTTPANPYMYRSAAEPCMS-------SSMSSS 461
            |...::                   .||..    ::.|:|:.|.::....:|       |::.::
  Fly   361 SLDEDIEESSPIKVKKKDDGQVIKKEAVST----SSKASPFGYENSTPSLVSFRRDSDASAVGNA 421

  Fly   462 IATLRLKAKQHASAGFGSPYSAPSPVSRSNS-----AGLSACQYTGVGVTDVVXENALGALLNQH 521
            ..:..:..|:..||  .:..:.|:|:|.|||     .|.:...:.|...:... :......|:..
  Fly   422 PTSKAVGKKRFQSA--ANAIATPTPLSDSNSGNGSGGGPAGGYFPGYYPSPKQQQQVQQQQLHPQ 484

  Fly   522 Q-----------------------HHLQHFSGGSVGG---SGVPNGMQQHSGNMLHHSNLGLDH- 559
            |                       ||..|....::.|   |..|:....|..:.....|   ||
  Fly   485 QQQLPQQQPQDYYGKYDIEFAASPHHNPHNKQQALHGEYLSPKPSSANFHQNSQQQQQN---DHF 546

  Fly   560 ----SDLGLVGGGP-SNHQDEGNHSLE--------GSNKSPMEAPLANSSNNNNN---DN 603
                :|   ..|.| .|||.:.:|..:        .::.:..|.|:...||.||.   ||
  Fly   547 YYNYND---TNGTPYLNHQQQHHHHAQHHQQQQHHQNHVADFEGPVNGPSNFNNGAYYDN 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	28/55 (51%)
pb	NP_476669.3	Homeodomain	199..255	CDD:459649	28/55 (51%)