Protein Alignment Ptx1 and cdx1

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 205
• Identity: 54/205 - (26%)
• Similarity: 79/205 - (38%)
• Gaps: 44/205 - (21%)

  Fly   137 SSLSHLHHSAGQDLVGGYSQHPHH----TVVPPHTPKHEPLEKLRIWAETGDFRDSHSSMTAVAN 197
            |.....||      |.|.:..|||    .....:||..|.      |...|. ....||......
 Frog    38 SDFPSYHH------VPGINSDPHHGQPGGTWSSYTPSRED------WHPYGP-GPGASSANPAQI 89

  Fly   198 SLDSTHLNNFQ--------TSSTSSIS--NRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSG 252
            |...:..|..|        .|..||:|  :.|..|::....:..|.:.| :.:|:|
 Frog    90 SFSPSDYNPVQPPGPGLLPPSLNSSVSPLSPSAQRRNLYEWMRRTGVPT-STNSNG--------- 144

  Fly   253 EEPKNDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRA 317
                   |.:.:.:.|..:|..|..|||..|..:||..:..:.|:|....|||.:|::||:||||
 Frog   145 -------KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAASLALTERQVKIWFQNRRA 202

  Fly   318 KWRKRERNAM 327
            |.||..:..|
 Frog   203 KERKVNKKKM 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	22/55 (40%)
cdx1	NP_989416.1	Caudal_act	13..141	CDD:461413	26/116 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		21/90 (23%)
		Homeodomain	151..206	CDD:459649	22/54 (41%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		7/20 (35%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		5/10 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		4/10 (40%)