Protein Alignment Ptx1 and Lim3

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001260559.1
• Gene: Lim3 / 35184
• FlyBaseID: FBgn0002023
• Length: 555
• Species: Drosophila melanogaster
• Alignment Length: 599
• Identity: 121/599 - (20%)
• Similarity: 189/599 - (31%)
• Gaps: 190/599 - (31%)

  Fly   110 HLHSHHSLHDSSSS----VSISPAISSLMPISSLS-------HLHHSAGQD-----------LVG 152
            |.|.|...|.....    ..:...:.....:|::.       |:|....|.           |||
  Fly    15 HQHQHQLQHPPQQQPHPHQQLQHPLQQQQHLSAMDNHQQHQPHIHQQQQQQQQLPPTPQASHLVG 79

  Fly   153 G---YSQHPHHT--VVPPHTPKHEPLEKL-------------------------------RIW-- 179
            |   ..|||||.  .|....|..|.:..|                               |.|
  Fly    80 GQQQQQQHPHHNHLAVDQDDPNPELVLALISRNRALEATIPKCGGCHELILDRFILKVLERTWHA 144

  Fly   180 -----------------AETG------DFRDSHSSMTA-----------VANSLDST-HLNNFQT 209
                             |..|      ||...:.:..:           |..:.|:. ||..|..
  Fly   145 KCLQCSECHGQLNDKCFARNGQLFCKEDFFKRYGTKCSACDMGIPPTQVVRRAQDNVYHLQCFLC 209

  Fly   210 SSTSSISNRS------RDRK-DGNRSVNETTIKTENISSSGHDEPMTTSGEEPKNDKKNKRQRRQ 267
            :..|...|..      .||| ...|...|...|...:..|       ..|::|        .:|.
  Fly   210 AMCSRTLNTGDEFYLMEDRKLICKRDYEEAKAKGLYLDGS-------LDGDQP--------NKRP 259

  Fly   268 RTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAAVA 332
            ||..|::||:.|:..::.:..|....||:::..|.|....|:|||:|||||.::.:::|.....:
  Fly   260 RTTITAKQLETLKTAYNNSPKPARHVREQLSQDTGLDMRVVQVWFQNRRAKEKRLKKDAGRTRWS 324

  Fly   333 AADFKSGFGTQFMQPFADDSL--------YSSYPYNNWTKVPSPLGTKPFPWPVNPLGSMVAGNH 389
            .. |:|..|.  ..|..|..|        |.|:                              :|
  Fly   325 QY-FRSMKGN--CSPRTDKFLDKDELKVDYDSF------------------------------SH 356

  Fly   390 HQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSNTSNVGAVGAPCP----YTTPANP--YMYRS 448
            |..|.:.::|...|:....:..|:....|..|.|.:....:..:|.|    :|..:.|  .:|.:
  Fly   357 HDLSNDSYSTVNLGLDEGASPHSIRGSYMHGSSSPSQYPPSSRSPPPVGQGHTFGSYPDNIVYTN 421

  Fly   449 AAEPCMSSSMSSSIATLRLKAKQH-------ASAGFGSPYSAPSPVSRSNSAGLSACQYTGVGVT 506
             .:..:.||:.:|.|..||.:..:       :|...|.|...|||.|....:          |.|
  Fly   422 -IDQAVGSSLHASKAHHRLHSSNNVSDLSNDSSPDQGYPDFPPSPDSWLGDS----------GST 475

  Fly   507 DVVXENALGALLNQHQHHLQHFSGGSVGG---SGVPNGMQQHSGNMLHHSNLGLDHSDL---GLV 565
            :.. .|......:...|:..:.|||..||   |..||  ....|....:|||.|.:.::   .|:
  Fly   476 NTTSANNNANNNSSSSHNNNNSSGGGSGGVSVSTAPN--PSAPGVHYXYSNLLLRYFEMQSRSLL 538

  Fly   566 GGGPSNHQDEGNHS 579
            .......|....||
  Fly   539 LAAAQQQQQHQPHS 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	21/55 (38%)
Lim3	NP_001260559.1	LIM1_Lhx3_Lhx4	122..173	CDD:188754	4/50 (8%)
		LIM2_Lhx3_Lhx4	181..236	CDD:188762	11/54 (20%)
		Homeodomain	257..313	CDD:459649	21/55 (38%)