Protein Alignment Ptx1 and unc-4

DIOPT Version :9

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001285389.1
• Gene: unc-4 / 32757
• FlyBaseID: FBgn0024184
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 139/613 - (22%)
• Similarity: 203/613 - (33%)
• Gaps: 189/613 - (30%)

  Fly    89 SSGSTGSSTVNGGGSSTSGTEHLHSHHSLHDSSSSVSISPAISSLMPISSLSHLHH-SAGQDLVG 152
            |.|.|.....|...||.|...:.|::::.:.|...:......||....:|:.:.|. :|||.|:|
  Fly     6 SEGDTKKFLTNNNNSSASRNNNSHNNNNNNHSPKEIPEETGRSSSTSSNSIPNAHRTNAGQHLLG 70

  Fly   153 GY---------------SQHPHHTV-----------------VPPHTP-----------KHEP-L 173
            |.               |:..|.|.                 |||..|           .:.| |
  Fly    71 GSPSSACSTSVSGCGMPSEGLHPTAALQLYAAAAQLAPNGVRVPPWGPFLQFGVPGVFGPNGPFL 135

  Fly   174 EKLRIWAETGDFRDSHSSMTAVANSLDSTHLNNFQTS----STSSISNRSRDRKDGNRSVNETTI 234
            .:.|..|.:.....:.::..|.|..:.:.:.:|...:    |.:::.|.|..:.....:|..|..
  Fly   136 GRPRFDAASAGGHPNSAAAAAAATQMAAVNASNAFANLTGLSAAALRNVSAAQTTAVAAVASTVA 200

  Fly   235 KTENISSSGHDEPMTTSG--EEPKN-----------DKKNKRQRRQRTHFTSQQLQELEHTFSRN 286
            ..::....|:.:.:..:|  .|..|           |....::||.||:|.|.||:|||..||.:
  Fly   201 TIQHRLMIGNRQSLPPAGPPSEGSNEDGGFPGDGDDDSSAAKRRRSRTNFNSWQLEELERAFSAS 265

  Fly   287 RYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRE-------RNAMNAAVAAADFKSGFGTQF 344
            .|||:..||.:||..:|.|:||.|||:|||||.||||       |.|.||.....   ||
  Fly   266 HYPDIFMREALAMRLDLKESRVAVWFQNRRAKVRKREHTKKGPGRPAHNAQPQTC---SG----- 322

  Fly   345 MQPFADDSL--------------------------------------YSSYPYNNWTKVPSPL-- 369
             :|...:.|                                      |.|....|.|...|.|
  Fly   323 -EPIPPNELKAKERARRRKKLAKAIDRQARKLQAKGITVDLEALKAEYISQHKANGTFSDSDLED 386

  Fly   370 ----------------GTKPFPWPVNPLG---------SMVAGNHHQNSVNCFNTGASGVAVSMN 409
                            |......||. ||         ....|....:|::|   |..|...|..
  Fly   387 DGIQIDVVGGTDSDDEGDSDAVSPVR-LGGGGGGGGGTGGGGGGGASSSLHC---GLDGDGDSSR 447

  Fly   410 NASMLPGSMGSSLSNTSNVGAVGAPCPYTTPANPYMYRSAAEPCMSSSMSSSIATLRLKAKQHAS 474
            ..|.:.|.           |::|:|            .|.|.|.|.|:.:.....|. ....:.|
  Fly   448 AGSFIGGG-----------GSLGSP------------SSVAPPSMLSNGAVQFGKLE-PMDGNES 488

  Fly   475 AGFGSPYSAPSPV-------------SRSNSAGLSACQYTGVGVTDVVXENALGALLNQHQHHLQ 526
            ........:|.|:             |.....||...|..|.|      .:..|...|.|||||.
  Fly   489 EERDRERDSPKPLLFPAKAFHQLNLQSSQQHHGLVVGQGQGSG-----SGHGHGHQHNHHQHHLH 548

  Fly   527 HFSGGSVGGSGVPNGMQQHSGNMLHHSN 554
            |.|..:...:.|.|.:.|.|...:..||
  Fly   549 HGSASASAAAAVANLVHQTSPISMRRSN 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeobox	268..320	CDD:278475	30/51 (59%)
unc-4	NP_001285389.1	Homeobox	246..299	CDD:278475	30/52 (58%)
		NK	<327..>368	CDD:302627	1/40 (3%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450910
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840