Protein Alignment Ptx1 and Vsx1

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_572232.2
• Gene: Vsx1 / 31470
• FlyBaseID: FBgn0263511
• Length: 837
• Species: Drosophila melanogaster
• Alignment Length: 694
• Identity: 155/694 - (22%)
• Similarity: 238/694 - (34%)
• Gaps: 195/694 - (28%)

  Fly     3 RSSAVGGCGGGGGLGVGVVTSSATALGPGGLTNGGGGVVSGALNGLEAMSAESTGLCLQDLVSAG 67
            ::|:..|.||.||.|.|               :|||...|..|..|.:.:|.          :.|
  Fly   207 KNSSSSGNGGSGGSGSG---------------SGGGNPTSNGLGHLGSPTAS----------NGG 246

  Fly    68 TANGAGSAGSAESATTTSTALSSGSTGSSTVNG--GGSSTSGTEHLHSHHS----LHDSSSSVSI 126
            :..|||..||...:.|      |||..|::.||  ||||.|.:.....|||    .|..:::.
  Fly   247 SGGGAGVGGSGGGSGT------SGSNSSTSGNGGNGGSSGSRSSPAGPHHSAALAAHQHAAAA-- 303

  Fly   127 SPAISSLMPISSLSHLHHSAGQDLVGGYSQHPHHTVVPPHTPKHEPLEKLRIWAETGDFRDSHSS 191
                      ::.:| ||:|    ....:.|.||.....|...|..:.             :|::
  Fly   304 ----------AAAAH-HHAA----AAAAAHHAHHAHAQAHAHAHAHVH-------------AHAA 340

  Fly   192 MTAVANSLDSTHLNNFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPK 256
            ..|.|....:.|...|..::             |....|..::    :::.|.|..:...|..|.
  Fly   341 HAAHAAHAHAHHAEAFLGAA-------------GGAGGNPNSL----LAAHGGDVLVGPGGTGPG 388

  Fly   257 NDKKNKRQRRQRTHFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRK 321
            ..||||| |..||.|||.||:|||..|....|||:|.||.::|.|.|.|.|::||::||||||||
  Fly   389 GKKKNKR-RHGRTIFTSSQLEELEKAFKEAHYPDVSARELLSMKTGLAEDRIQVWYQNRRAKWRK 452

  Fly   322 RERNAMNAAVAAADFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLG---------------- 370
            .|:...::...|.....|...:...|..:..:.|:  ..:.:..|..||
  Fly   453 TEKCWGHSTKMAEYGLYGAMVRHSLPLPETIIKSA--KEDESVAPWLLGMHKKSLEAAELLKSDE 515

  Fly   371 -TKPFPWPVNPLGSMVAGNHHQNSVNCFNTG---------ASGVAVSMNNASMLPGSMGSSLSNT 425
             .:..|...:...|..||:.|.:.::.|:..         |:|.|          |..|....:.
  Fly   516 SDRETPTSDDTNTSYSAGSTHNSPISSFSISRLLFDAPPPAAGSA----------GGKGHHHHHH 570

  Fly   426 SNVGAVGAPCPYTTPANPYMYRSAAEPCMSSSMSSS------IATLRLKAKQHASAGFGSPYSAP 484
            .:.|...|.......|:.:|.....:..........      .|...|:.:|.|..|.||
  Fly   571 HHKGHHHAHVHAQAQAHAHMLLHHQQQQQQQQQQQQHHHHLHAAENSLQQQQVAGTGSGS----- 630

  Fly   485 SPVSRSNSAGLSACQYTGVGVTDVVXENALGALLNQHQHHLQHFSGGSVGGSGVPNGMQQ----- 544
                     |..:...||.|.|... .:....  .||.||||................||
  Fly   631 ---------GSGSGSGTGAGSTGPPAHHPYNQ--QQHLHHLQQLQQQQQQQQQQAQQQQQHHHHQ 684

  Fly   545 --HSGNMLHHSNLGLDHSDLGL------------------------------------VGGGPSN 571
              ||.:.:||.|....:::..:                                    :....:.
  Fly   685 HHHSVHHMHHHNAAAGYAEAAVAAAAAAAAVAAAANARNAAAAAAVAAASASASAAVTIAESEAE 749

  Fly   572 HQDEGNHSLEGSNKSPME---APLANSSN-NNNNDND---DEDV 608
            .:.:....:|......:|   .|:.|.:| ||.:||:   |.||
  Fly   750 EEQDDIEDMELDKDCEVEEDVEPVDNDTNTNNEHDNECDADADV 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	31/55 (56%)
Vsx1	NP_572232.2	Homeodomain	395..452	CDD:459649	32/57 (56%)