Protein Alignment Ptx1 and Vsx2

DIOPT Version :10

• Sequence 1: NP_001138130.2
• Gene: Ptx1 / 43664
• FlyBaseID: FBgn0020912
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 657
• Identity: 151/657 - (22%)
• Similarity: 235/657 - (35%)
• Gaps: 156/657 - (23%)

  Fly    54 ESTGLCLQDLVSAGT--ANGAGSAGSAESAT---------TTSTALSSGSTGSSTVNGG-GSSTS 106
            |..||.:.....|.|  ...||:..:.|..|         |.:||.:|.:|.::..|.. |:.||
  Fly    11 ELLGLAVAAATEAPTDLTTTAGATVAKERQTPTPPKTTNATMATAATSAATAATPTNAAEGNLTS 75

  Fly   107 GTE-------------HLHSHHSLHDSSSSVSISPA------------ISSLMP--ISSLSHLHH 144
            .:|             |...||..:.....::::.|            .::.||  :::..|.||
  Fly    76 VSEPQQQPQQQQQEQQHHQPHHHQYREHHQMTMAAASRMAYFNAHAAVAAAFMPHQLAAAVHHHH 140

  Fly   145 SAGQDLVGGYSQHPHHTVVPPH-----TPKHEPLEKLRIWAETGDFRDSHSSMTAVANSLDSTHL 204
            .      ..:..||||....||     .|...|::          ....|.....:.::.....|
  Fly   141 Q------HQHQHHPHHHPHHPHGAVGGPPPPPPMQ----------HHHPHHPHHPLLHAQGFPQL 189

  Fly   205 NNFQTSSTSSISNRSRDRKDGNRSVNETTIKTENISSSGHDEPMTTSGEEPKNDKKNKRQRRQRT 269
            .:|...:.:.:......:..|..|:|                   ..|..|.:.||.|::|..||
  Fly   190 KSFAAGAGTCLPGSLAPKDFGMESLN-------------------GFGVGPNSKKKKKKRRHSRT 235

  Fly   270 HFTSQQLQELEHTFSRNRYPDMSTREEIAMWTNLTEARVRVWFKNRRAKWRKRERNAMNAAVAAA 334
            .|||.||::||..|....|||:..||.:::.|.|.|.|::|||:||||||||.|:....:.:.|.
  Fly   236 IFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWGGSTIMAE 300

  Fly   335 DFKSGFGTQFMQPFADDSLYSSYPYNNWTKVPSPLGTKP-------------------FPWPVNP 380
            ....|...:...|..|..|.|:  .:|....|..||.:.                   .....:.
  Fly   301 YGLYGAMVRHSLPLPDTILKSA--KDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVSDHEDS 363

  Fly   381 LGSMVAGNHHQNSVNCFNTGASGVAVSMNNASMLPGSMGSSLSN----TSNVGAVG-APCPYTTP 440
            .||..|.:...:...|....:|  ..|:|..|..|.|..:|.|.    ||..|..| |....|||
  Fly   364 AGSKSAHSEDLSRSRCHALSSS--TESLNVVSPAPSSCPTSASTSAPPTSTSGYAGAASSAATTP 426

  Fly   441 ANPYMYRSAAEPCMS----SSMSSSIATLRLKAKQHAS--AGFGSPYSAPSPVS------RSNSA 493
            .......|::.|.:.    |........|:.:.:|.||  .|.|:..:..:|.|      .:|:|
  Fly   427 TGASTTNSSSSPHIELGSPSPQQQQHLQLQQQQQQQASLYLGAGAVVTGCAPPSYHPLLDAANAA 491

  Fly   494 GLSAC----QYTGVGVTDVVXENALGALLNQHQHHLQHFSGGSVGGSGV-------------PNG 541
            |..|.    .:..:..|.|.   |..|...|||...|.....:....|:             |:.
  Fly   492 GAGAAASSKDFHMIMNTAVAA--AAAAAQQQHQQQQQQQQQATATAPGLHAHNLAAALMEHDPDA 554

  Fly   542 M------------QQHSGNMLHHSNLGLDHSDLGLVGGGPSNHQDEGNH---SLEGSNKSPMEAP 591
            .            |:|...:|::..|.|   .:.....|.:..||..:.   |.|.:|.||:..|
  Fly   555 FRNNSIACLRAKAQEHQARLLNNGGLFL---QVRRFAQGQAQIQDPSDMLKLSEEHNNNSPIPIP 616

  Fly   592 LANSSNN 598
            .|:|:.|
  Fly   617 PAHSTVN 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ptx1	NP_001138130.2	Homeodomain	265..321	CDD:459649	29/55 (53%)
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	29/56 (52%)
		OAR	556..572	CDD:461067	2/15 (13%)